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Displaying results 4671 - 4680 of 10000 in total
  1. Target

    5-hydroxytryptamine 2 receptor

    go.drugbank.com/bio_entities/BE0004881
    TargetHumans

    Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD) (PubMed … phospholipase C-beta, releasing diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) second messengers that modulate the activity of phosphatidylinositol 3-kinase and promote the release of Ca(2+

    Synonyms: 5-HT-2Function: 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding, 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding
  2. Target

    5-hydroxytryptamine receptor 2

    go.drugbank.com/bio_entities/BE0004957
    TargetHumans

    Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD) (PubMed … phospholipase C-beta, releasing diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) second messengers that modulate the activity of phosphatidylinositol 3-kinase and promote the release of Ca(2+

    Synonyms: 5-HT-2Function: 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding, 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding
  3. Target

    Mitochondrial 2-oxodicarboxylate carrier

    go.drugbank.com/bio_entities/BE0008678
    TransporterHumans

    Can transport 2-oxoadipate (2-oxohexanedioate), 2-oxoglutarate, adipate (hexanedioate), glutarate, and to a lesser extent, pimelate (heptanedioate), 2-oxopimelate (2-oxoheptanedioate), 2-aminoadipate ( … 2-aminohexanedioate), oxaloacetate, and citrate (PubMed:11083877).

    Polypeptides: Mitochondrial 2-oxodicarboxylate carrierSynonyms: Mitochondrial 2-oxoadipate carrier
  4. Target

    Growth/differentiation factor 2

    go.drugbank.com/bio_entities/BE0010630
    TargetHumans

    Potent circulating inhibitor of angiogenesis. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG

    Polypeptides: Growth/differentiation factor 2Synonyms: GDF-2
  5. Target

    Bromodomain-containing protein 2

    go.drugbank.com/bio_entities/BE0012869
    TargetHumans

    Chromatin reader protein that specifically recognizes and binds histone H4 acetylated at 'Lys-5' and 'Lys-12' (H4K5ac and H4K12ac, respectively), thereby controlling gene expression and remodeling chromatin structures (PubMed:17148447, P...

    Polypeptides: Bromodomain-containing protein 2
  6. Target

    Extracellular sulfatase Sulf-2

    go.drugbank.com/bio_entities/BE0016611
    TargetHumans

    Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity (PubMed:12368295, PubMed:30788513, PubMed:35294879). It can remove sulfate from the C-6 position of glucosamine within specific subregions of intact...

    Polypeptides: Extracellular sulfatase Sulf-2Synonyms: hSulf-2
  7. Target

    Nicotinamide riboside kinase 2

    go.drugbank.com/bio_entities/BE0019876
    TargetHumans

    Catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). Reduces laminin matrix deposition and cell adhesion to lami...

    Polypeptides: Nicotinamide riboside kinase 2Synonyms: NRK 2, RNK 2
  8. Target

    LanC-like protein 2

    go.drugbank.com/bio_entities/BE0020245
    TargetHumans

    Necessary for abscisic acid (ABA) binding on the cell membrane and activation of the ABA signaling pathway in granulocytes

    Polypeptides: LanC-like protein 2
  9. Target

    Lysyl oxidase homolog 2

    go.drugbank.com/bio_entities/BE0021305
    TargetEnzymeHumans

    Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine) (PubMed:27735137). Acts as a transcription corepressor and specifically mediates deamina...

    Polypeptides: Lysyl oxidase homolog 2Synonyms: Lysyl oxidase-like protein 2, Lysyl oxidase-related protein 2
  10. Drug

    Pamidronic acid

    go.drugbank.com/drugs/DB00282
    ApprovedInvestigational

    Pamidronic acid is a second generation, nitrogen containing bisphosphonate similar to [neridronic acid] and [alendronic acid].[A203111] Pamidronic acid was first described in the literature in 1977.

    Products: Pamidronate Disodium Omega 6 mg/ml, Pamidronate Disodium Omega 9 mg/ml