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Displaying results 4671 - 4680 of 8700 in total
  1. Drug

    Dichlorvos

    go.drugbank.com/drugs/DB11397
    ExperimentalVet approved

    Dichlorvos or 2,2-dichlorovinyl dimethyl phosphate is a drug of the _organophosphate_ class, frequently used as an insecticide for the control of indoor pests and for the protection of stored products … Dichlorvos is found in urban waterways and its toxicity may impact humans, leading to poisoning, neurotoxicity, and cancer.

  2. Drug

    Cat dander extract

    go.drugbank.com/drugs/DB13904
    Approved

    Cat dander extract can be used in immunotherapy in individuals who cannot avoid exposure to cat allergens to initiate hyposensitization. … An allergic reaction to cats is induced by the presence of antigen-specific IgE antibodies that are bound to specific receptors on mast cells and basophils.

  3. Drug

    Olesoxime

    go.drugbank.com/drugs/DB05185
    Investigational

    For example, it has demonstrated the ability to prevent neurodegeneration, enhance nerve function and accelerate neuroregeneration following nerve trauma.[A3282,A253233]

  4. Drug

    Bisegliptin

    go.drugbank.com/drugs/DB06127
    Investigational

    Bisegliptin is a compound for the treatment of type 2 diabetes. … It is an orally active, dipeptidyl peptidase-IV (DPPIV) inhibitor which lowers blood glucose levels by blocking the degradation of the hormone GLP-1 thereby stimulating glucose-dependent insulin secretion

  5. Drug

    Apronalide

    go.drugbank.com/drugs/DB13221
    Approved

    Apronalide has been withdrawn from the market in many other countries due to patient development of thrombocytopenic purpura [A174814].

  6. Drug

    Recombinant Bacterial ACE2 Receptors-like Enzyme

    go.drugbank.com/drugs/DB15741
    Investigational

    It is being investigated for treating hypertension, myocardial fibrosis, and cardiac dysfunction. … ._ The molecule, an Angiotensin Converting Enzyme 2 (ACE2)-like enzyme, shares structural similarities to the mammalian ACE2. B38-CAP is an ACE2-like enzyme which decreases angiotensin II levels.

  7. Drug

    AMG 108

    go.drugbank.com/drugs/DB05545
    Investigational

    AMG 108 was investigated for use as an antirheumatic agent.

    Categories: Interleukin-1 Receptor Antagonist
  8. Target

    UDP-glucuronosyltransferase 1A1

    go.drugbank.com/bio_entities/BE0003541
    EnzymeTransporterTargetHumans

    Involved in the glucuronidation of the AGTR1 angiotensin receptor antagonist losartan, a drug which can inhibit the effect of angiotensin II (PubMed:18674515).

    Synonyms: hUG-BR1
  9. Drug

    Aluminium

    go.drugbank.com/drugs/DB01370
    ApprovedInvestigationalWithdrawn

    A metallic element that has the atomic number 13, atomic symbol Al, and atomic weight 26.98.

  10. Drug

    CERE-120

    go.drugbank.com/drugs/DB05637
    Investigational

    CERE-120 is an investigational drug consisting of an adeno-associated virus (AAV) that was engineered to carry the human gene for neurturin, a neurotrophic (growth) factor. … It was under investigation in clinical trials for the treatment of Parkinson's Disease.