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ATP-dependent 6-phosphofructokinase, muscle type
go.drugbank.com/bio_entities/BE0012586TargetHumansCatalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
Synonyms: PFK-A, 6-phosphofructokinase type AEndothelin-1 receptor
go.drugbank.com/bio_entities/BE0000521TargetHumansReceptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. … The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3
Polypeptides: Endothelin-1 receptorSynonyms: Endothelin receptor type A, ET-APhospholipase A1
go.drugbank.com/bio_entities/BE0002041TargetEscherichia coli (strain K12)Has broad substrate specificity including hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities. Strong expression leads to outer membrane breakdown and cell death; is dormant ...
Synonyms: DR-phospholipase A, Outer membrane phospholipase ADesloratadine
go.drugbank.com/drugs/DB00967ApprovedInvestigationalDesloratadine is a second generation, tricyclic antihistamine that which has a selective and peripheral H1-antagonist action. … It is the active descarboethoxy metabolite of loratidine (a second generation histamine).
Synonyms: 8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine, 8-chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo(5,6)cyclohepta(1,2-b)pyridineMixtures: DESLAIR® - D, DESLODEX ® D CÁPSULASBetamethasone
go.drugbank.com/drugs/DB00443ApprovedInvestigationalVet approvedBetamethasone is a long-acting corticosteroid with immunosuppressive and antiinflammatory properties. … [A192444] It can be used topically to manage inflammatory skin conditions such as eczema, and parenterally to manage several disease states including autoimmune disorders.
Synonyms: 9-Fluoro-16β-methylprednisoloneMixtures: Amolg A, SAEROGENTA-A CREAMInterferon alpha-2
go.drugbank.com/bio_entities/BE0003450TargetHumansProduced by macrophages, IFN-alpha have antiviral activities
Synonyms: LeIF A, Interferon alpha-AEnuresis
go.drugbank.com/conditions/DBCOND0018540Drugs: ImipramineSynonyms: Enuresis not due to a substance or known physiological conditionPhenylephrine
go.drugbank.com/drugs/DB00388ApprovedInvestigationalPhenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate the pupil,[L9413] and induce local vasoconstriction. … [A187376] Phenylephrine was granted FDA approval in 1939.[L9413]
Synonyms: l-(3-Hydroxyphenyl)-N-methylethanolamine, (−)-m-hydroxy-α-(methylaminomethyl)benzyl alcoholInternational brands: AK-Dilate, AK-NefrinDe Novo Triacylglycerol Biosynthesis TG(10:0/a-13:0/a-13:0)
smpdb.ca/view/SMP0031934MetabolicA triglyceride (TG, triacylglycerol, TAG, or triacylglyceride) is an ester derived from glycerol and three fatty acids. … Last, the enzyme diacylglycerol O-acyltransferase synthesizes triacylglycerol from diacylglycerol and a fatty acyl-CoA.
De Novo Triacylglycerol Biosynthesis TG(10:0/a-13:0/a-25:0)
smpdb.ca/view/SMP0031938MetabolicA triglyceride (TG, triacylglycerol, TAG, or triacylglyceride) is an ester derived from glycerol and three fatty acids. … Last, the enzyme diacylglycerol O-acyltransferase synthesizes triacylglycerol from diacylglycerol and a fatty acyl-CoA.