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Idursulfase
go.drugbank.com/drugs/DB01271ApprovedInvestigationalIdursulfase is a purified form of human iduronate-2-sulfatase, a lysosomal enzyme. Idursulfase is produced by recombinant DNA technology in a human cell line. … Idursulfase is a 525-amino acid glycoprotein with a molecular weight of approximately 76 kilodaltons.
Synonyms: Alpha-L-iduronate sulfate sulfatase, Iduronate 2-sulfataseProducts: ELAPRASE 2 MG/ML İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET, ELAPRASE ®Urea
go.drugbank.com/drugs/DB03904ApprovedInvestigationalA compound formed in the liver from ammonia produced by the deamination of amino acids. … It is the principal end product of protein catabolism and constitutes about one half of the total urinary solids.
Mixtures: HYDROCORTISONE 1% ET UREA 5% CREAM, Ti-U-lac LotionProducts: Avenaster Fungal Nail Care Duo Set (day), UBIT TABLET 100 MGPitavastatin
go.drugbank.com/drugs/DB08860ApprovedInvestigational[A181087, A181406] Evidence has shown that even for low-risk individuals (with <10% risk of a major vascular event occurring within 5 years) statins cause a 20%-22% relative reduction in major cardiovascular … events (heart attack, stroke, coronary revascularization, and coronary death) for every 1 mmol/L reduction in LDL without any significant side effects or risks.
Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesProducts: Trolise 1 mg Filmtabletten, PITAMIN 1 MG EFERVESAN TABLET, 30 ADETTechnetium Tc-99m mebrofenin
go.drugbank.com/drugs/DB09137ApprovedWithdrawnTechnetium Tc 99m Mebrofenin is a diagnostic radiopharmaceutical composed of diisopropyl-iminodiacetic acid (DISIDA) attached to a technetium-99m ion. … -99m as it decays.
Synonyms: Bis(2-[[2-(3-bromo-2,4,6-trimethylanilino)-2-oxoethyl]-(carboxymethyl)amino]acetate) technetiumCategories: Compounds used in a research, industrial, or household settingDextran
go.drugbank.com/drugs/DB09255ApprovedInvestigationalVet approvedDextran is a polysaccharide that differs from others in that its glucose units are joined together 1:6 glucoside links. … [T121] Dextran 40 is a sterile, nonpyrogenic preparation of low molecular weight dextran (average mol. wt. 40,000) in 5% Dextrose Injection or 0.9% Sodium Chloride Injection.
Salts: Dextran 75, Dextran sulfate sodium (MW 5000)Mixtures: RHEOMACRODEX EN SOLUCIÓN GLUCOSADA, RHEOMACRODEX EN SOLUCIÓN SALINA ISOTÓNICAIobitridol
go.drugbank.com/drugs/DB12407ApprovedWithdrawnIobitridol has been used in trials studying the diagnostic of Diagnostic Imaging, Coronary Artery Disease, Type 2 Diabetes Mellitus, and Coronary Atherosclerosis.
Categories: Compounds used in a research, industrial, or household setting, X-Ray Contrast Media, IodinatedProducts: XENETİX 300 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 100 ML, Xenetix 250 (250 mg Jod/ml) - Parenterale RöntgenkontrastmittellösungAminophylline
go.drugbank.com/drugs/DB01223ApprovedInvestigationalAminophylline is a drug combination that contains theophylline and ethylenediamine in a 2:1 ratio. … Once in the body, theophylline is released and acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator.
Categories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexProducts: อมิโนฟิลลีน 1 1/2 เกรน, TECAR 240 MG/10 ML IV INFUZYONLUK COZELTI, 6 ADETValaciclovir
go.drugbank.com/drugs/DB00577ApprovedInvestigationalIt was initially approved by the FDA in 1995 [FDA label] and marketed by GlaxoSmithKline [L5671]. Valacyclovir is the L-valine ester of aciclovir. … It is a member of the purine (guanine) nucleoside analog drug class [F3949]. This class of drugs forms an important part of hepatitis, HIV, and cytomegalovirus drug regimens [A175900].
Synonyms: L-Valine ester with 9-((2-hydroxyethoxy)methyl)guanine, L-Valine, 2-((2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy)ethyl esterCategories: Heterocyclic Compounds, 2-RingTuberculin purified protein derivative
go.drugbank.com/drugs/DB11601ApprovedTuberculin Purified Protein Derivative (PPD) is a sterile aqueous solution of a purified protein fraction for intradermal administration as an aid in the diagnosis of tuberculosis. … The purified protein fraction is isolated from culture media filtrates of a human strain of Mycobacterium tuberculosis. It is included in the World Health Organization's List of Essential Medicines.
Categories: Compounds used in a research, industrial, or household settingProducts: PPD TÜBERKÜLIN 5 TU/ 0.1 ML INTRADERMAL ENJEKSIYONLUK ÇÖZELTI IÇEREN FLAKON, 1 ADET, PPD TÜBERKÜLİN 100 TU/2 ML İNTRADERMAL ENJEKSİYONLUK ÇÖZELTİ, 1 ADETAvelumab
go.drugbank.com/drugs/DB11945ApprovedInvestigationalAvelumab is a human IgG1 lambda monoclonal antibody that binds programmed cell death ligand-1 (PD-L1) to block its interaction with its receptors found on T cells and antigen-presenting cells. … [A261496] On September 18 and December 18 of the same year, it was also granted approval by EMA [L48126] and Health Canada,[L48171] respectively.
Categories: PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitors, PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitorsProducts: BAVENCIO 200 MG/10 ML IV İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 FLAKON, BAVENCIO®