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Displaying results 4721 - 4730 of 10000 in total
  1. Drug

    Ilaprazole

    go.drugbank.com/drugs/DB11964
    Investigational

    Ilaprazole has been investigated in Helicobacter Infections.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: NOLTEC 10 MG GASTRO-REZİSTAN TABLET, 7 ADET
  2. Drug

    MK-7145

    go.drugbank.com/drugs/DB11968
    Investigational

    MK-7145 has been used in trials studying the treatment of Hypertension and Renal Insufficiency.

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  3. Drug

    Elamipretide

    go.drugbank.com/drugs/DB11981
    ApprovedInvestigational

    [A274436] Elamipretide is a synthetic tetrapeptide that selectively binds to cardiolipin, a phospholipid in the inner mitochondrial membrane. … Elamipretide is a mitochondrial cardiolipin binder being investigated for diseases involving mitochondrial dysfunction.

    Categories: MATE 1 Inhibitors
  4. Drug

    Ocrelizumab

    go.drugbank.com/drugs/DB11988
    ApprovedInvestigational

    such as a doctor's office. … [L42895] It is a second-generation recombinant humanized monoclonal IgG1 antibody that selectively targets B-cells that express the CD20 antigen.

    Products: OCREVUS® CONCENTRADO PARA SOLUCION PARA INFUSION 300MG/10ML, OCREVUS 300 MG/10 ML İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 2 ADET
  5. Drug

    Apabetalone

    go.drugbank.com/drugs/DB12000
    Investigational

    Apabetalone has been investigated for the treatment of Diabetes, Atherosclerosis, and Coronary Artery Disease.

    Categories: Heterocyclic Compounds, 2-Ring
  6. Drug

    Abemaciclib

    go.drugbank.com/drugs/DB12001
    ApprovedInvestigational

    Abemaciclib is an antitumor agent and dual inhibitor of cyclin-dependent kinases 4 (CDK4) and 6 (CDK6) that are involved in the cell cycle and promotion of cancer cell growth in case of unregulated activity

    Categories: MATE 1 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic IndexProducts: VERZENIO® 100 MG, VERZENIO® 150 MG
  7. Drug

    Nirogacestat

    go.drugbank.com/drugs/DB12005
    ApprovedInvestigational

    Nirogacestat is a small-molecule gamma-secretase inhibitor that was investigated as a potential treatment for desmoid tumors. … DeFi trial, where a confirmed objective response rate was observed to be 41% compared to 8% with the placebo.

    Categories: P-glycoprotein inhibitors, P-glycoprotein substrates
  8. Drug

    Isoflavone

    go.drugbank.com/drugs/DB12007
    ApprovedInvestigationalWithdrawn

    Soybean is an exceptionally rich source of dietary isoflavones, where the average isoflavone content is 1-2 mg/gram [A33103]. … Isoflavone is a soy phytoestrogen and a biologically active component of several agriculturally important legumes such as soy, peanut, green peas, chick peas and alfalfa [A33103].

    Mixtures: ISOFEM ® TABLETA RECUBIERTACategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  9. Drug

    GW-406381

    go.drugbank.com/drugs/DB12009
    Investigational

    GW-406381 has been used in trials studying the treatment of Pain, Trauma, Neurodynia, Dental Pain, and Hyperalgesia, among others.

    Categories: Heterocyclic Compounds, 1-Ring
  10. Drug

    PF-04457845

    go.drugbank.com/drugs/DB12012
    Investigational

    PF-04457845 is under investigation in Fear Conditioning. PF-04457845 has been investigated for the treatment of Tourette Syndrome and Cannabis Dependence.

    Categories: Heterocyclic Compounds, 1-Ring