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Displaying results 4761 - 4770 of 10000 in total
  1. Drug

    Bafilomycin A1

    go.drugbank.com/drugs/DB06733
    Experimental

    The most commonly utilized bafilomycin is bafilomycin A1. This is a useful tool as it can prevent the re-acidification of synaptic vesicles once they have undergone exocytosis. … The bafilomycins refer to a category of toxic macrolide antibiotics that are derivatives of Streptomyces griseus.

  2. Drug

    Linaprazan glurate

    go.drugbank.com/drugs/DB21534
    Investigational

    Linaprazan glurate is a small molecule drug. The usage of the INN stem '-prazan' in the name indicates that Linaprazan glurate is a proton pump inhibitor, not dependent on acid activation. … Linaprazan glurate is under investigation in clinical trial NCT07037875 (A Study Comparing the Effect and Safety of Linaprazan Glurate to Lansoprazole in Participants With Erosive Esophagitis (EE) Due

  3. Drug

    SP1049C

    go.drugbank.com/drugs/DB04978
    Experimental

    [A260416] It is designed to overcome drug resistance in a number of cancers. It has successfully completed Phase 1 trials. Phase 2 results are currently under final review. … Preliminary data, in its first clinically tested indication, shows that SP1049C is active in Stage IV non-resectable adenocarcinoma of the esophagus.

    Synonyms: doxorubicin with pluronics F-127 and L-61, Doxorubicin HCl with pluronic L-61 and pluronic F-127Categories: Compounds used in a research, industrial, or household setting
  4. Drug

    Boron

    go.drugbank.com/drugs/DB11203
    ApprovedInvestigational

    Boron (B) is a chemical element with an atomic number 5 that belongs in the Period 2 and Group 13 in the periodic table. … Natural boron exists in 2 stable isotopes however pure boron is hard to prepare due to contamination by different elements.

    Mixtures: Ribotin-E, Folitin-Z
  5. Drug

    TGAAC94

    go.drugbank.com/drugs/DB06175
    Investigational

    tgAAC94 is a recombinant adeno-associated virus serotype 2 (AAV2) vector containing the cDNA for a human tumor necrosis factor receptor (TNFR)-immunoglobulin (IgG1) Fc fusion (TNFR:Fc) gene. … The Health Recombinant DNA Advisory Committee (RAC) concluded that a possible role of the gene transfer in this clinical course could not definitively be excluded due to the lack of data. [A264038]

  6. Drug

    CCR5 mAb

    go.drugbank.com/drugs/DB05906
    Experimental

    CCR5 mAb is a fully human monoclonal antibody that specifically recognizes and binds the chemokine receptor CCR5, which is known to be a key facilitator of infection with human immunodeficiency virus ( … It was generated by HGS using the Abgenix XenoMouse technology.

  7. Drug

    Etelcalcetide

    go.drugbank.com/drugs/DB12865
    ApprovedInvestigational

    Etelcalcetide is a calcimimetic drug for the treatment of secondary hyperparathyroidism in patients undergoing hemodialysis. … Etelcalcetide was approved (trade name Parsabiv) for the treatment of secondary hyperparathyroidism (HPT) in adult patients with chronic kidney disease (CKD) on hemodialysis in February, 2017.

    Products: PARSABİV 5 MG/1 ML I.V. ENJEKSİYONLUK ÇÖZELTİ, 1 ADET, PARSABİV 5 MG/1 ML I.V. ENJEKSİYONLUK ÇÖZELTİ, 6 ADET
  8. Drug

    Clioquinol

    go.drugbank.com/drugs/DB04815
    ApprovedVet approvedWithdrawn

    Clioquinol was withdrawn in 1983 due to neurotoxicity.

    Synonyms: 5-Chlor-7-jod-8-hydroxy-chinolin, 5-Chloro-7-iodo-8-quinolinolMixtures: BETNOVATE-C % 0,1 + % 3 KREM, 5 GR, BETNOVATE-C % 0,1 + % 3 MERHEM, 5 GR
  9. Drug

    AT3022

    go.drugbank.com/drugs/DB05172
    Experimental

    AT3022, the Altea Therapeutics’s fentanyl citrate transdermal patch designed to provide safe and rapid management of moderate to severe chronic pain.

  10. Drug

    PRO 2000

    go.drugbank.com/drugs/DB05385
    Investigational

    This medicine does not cure HIV infection or AIDS and is being studied to reduce the risk of passing the virus to other people. … PRO 2000 is an investigational medicine that is not yet approved by the FDA for use outside of clinical trials.

    Synonyms: Naphthalene 2-sulfonate polymerCategories: Compounds used in a research, industrial, or household setting