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Chlorthalidone
go.drugbank.com/drugs/DB00310ApprovedInvestigationalheart failure when compared to [DB00722], [DB00381], or [DB00590]. … output and therefore overall reduction in blood pressure.
Mixtures: ATENOLOL COMP STADA 100MG, ATENOCOMP 1A 100MG/25MGProducts: Uridon Tab 100mg, Novo-thalidone Tab 100mgImatinib
go.drugbank.com/drugs/DB00619ApprovedInvestigational[L42220] Imatinib was approved on February 1st ,2001 by the FDA and November 7th, 2001 by the EMA; however, its European approval has been withdrawn in October 2023.[A263036,L49746,L49751] … Brian noted that "complete hematologic responses were observed in 53 of 54 patients with CML treated with a daily dosage of 300 mg or more and typically occurred in the first four weeks of therapy".
Products: IMATINIB EG, GLIVEC 100MGFlumazenil
go.drugbank.com/drugs/DB01205ApprovedInvestigationalreceptor complex, thereby reversing the effects of benzodiazepine on the central nervous system. … Fumazenil is an imidazobenzodiazepine derivative and a potent benzodiazepine receptor antagonist that competitively inhibits the activity at the benzodiazepine recognition site on the GABA/benzodiazepine
Categories: Compounds used in a research, industrial, or household settingProducts: LAUZENİL 1MG/10ML IV ENJEKSİYONLUK ÇÖZELTİ, 5 ADET, ANEXATE 1 MG/10 ML IV ENJ. ICIN COZ. ICEREN AMPUL, 5 ADETAllopurinol
go.drugbank.com/drugs/DB00437ApprovedInvestigationalThis disease has been well-documented in historical medical records and appears in the biographies of several prominent, historically recognized individuals [A175942]. … It was initially approved by the FDA in 1966 [L5674] and is now formulated by several manufacturers [L5677].
Products: ALLOPURINOLO EG, CLINT TABLET 100MGDronabinol
go.drugbank.com/drugs/DB00470ApprovedIllicitInvestigationalDue to its evidence as an appetite stimulant and an anti-nauseant, Dronabinol is approved for use in anorexia associated with weight loss in patients with AIDS and for the treatment of nausea and vomiting … CB2 receptors are mainly located in the peripheral nervous system and can be found on lymphoid tissue where they are involved in regulation of immune function [A32676].
Products: Marinol Cap 10mgSpironolactone
go.drugbank.com/drugs/DB00421ApprovedInvestigational[A178135, A261025] Spironolactone was developed in 1957, marketed in 1959, and approved by the FDA on January 21, 1960.[A178243]
Mixtures: SPIRO D TABLINEN 100MG, SPIRO COMP RATIO 50MG/20MGProducts: DIUXOTON® 100MG, ESPIRONOLACTONA 100MGParoxetine
go.drugbank.com/drugs/DB00715ApprovedInvestigational[L7712,L7715] A unique feature of this drug is that it is highly potent and selective in its inhibition of serotonin reuptake and has little effect on other neurotransmitters. … [T653] It was approved by the FDA in the early 1990s and marketed by SmithKline Beecham.
Products: PAROXETINA EG, Paxil Tab 10mgNalbuphine
go.drugbank.com/drugs/DB00844ApprovedInvestigationalIt appears to be an agonist at kappa opioid receptors and an antagonist or partial agonist at mu opioid receptors. … Nalbuphine is the only opioid analgesic that is not a controlled substance in the United States.
Synonyms: N-cyclobutylmethyl-4,5α-epoxy-3,6α,14-morphinantriolProducts: Nubain Injection 10mg/ml, INTAPAN INJECTION 1ML (10MG/ML) AMPOULEThiothixene
go.drugbank.com/drugs/DB01623ApprovedA thioxanthine used as an antipsychotic agent. Its effects are similar to the phenothiazine antipsychotics.
Products: Navane Capsules 10mgMetolazone
go.drugbank.com/drugs/DB00524ApprovedInvestigationalA quinazoline-sulfonamide that is considered a thiazide-like diuretic which is long-acting so useful in chronic renal failure. It also tends to lower blood pressure and increase potassium loss.
Products: Zaroxolyn Tab 10mg