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Hydroxyurea
go.drugbank.com/drugs/DB01005ApprovedInvestigational[A262601] Although clinical evidence on the efficacy of hydroxyurea in certain conditions exists, hydroxyurea is used sparingly in clinical settings, largely due to lack of knowledge and adherence, the … Hydroxyurea is a non-alkylating antineoplastic agent that was first synthesized in 1869 but was not characterized biologically until 1928.
Categories: Cytochrome P-450 CYP2D6 Inhibitors, Cytochrome P-450 Enzyme InhibitorsProducts: HYDREA 500 MG KAPSUL, 100 ADET, HYDMOXİA 500 MG SERT KAPSÜL, 100 ADETMebendazole
go.drugbank.com/drugs/DB00643ApprovedInvestigationalVet approvedA benzimidazole that acts by interfering with carbohydrate metabolism and inhibiting polymerization of microtubules. [PubChem]
Synonyms: (5-benzoyl-1H-benzimidazol-2-yl)-carbamic acid methyl esterProducts: MEBENDAZOL 100 MG / 5 ML SUSPENSION, MEBENDAZOL 100 MG/5 ML. SUSPENSIONCholecalciferol
go.drugbank.com/drugs/DB00169ApprovedInvestigationalNutraceuticalAppropriate levels of vitamin D must be upheld in the body in order to maintain calcium and phosphorus levels in a healthy physiologic range to sustain a variety of metabolic functions, transcription regulation … However, studies are also ongoing to determine whether or not cholecalciferol may also play certain roles in cancer, autoimmune disorders, cardiovascular disease, and other medical conditions that may
Synonyms: (3β,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol, (5Z,7E)-(3S)-9,10-secocholesta-5,7,10(19)-trien-3-olMixtures: Calcium With Vitamin D 200 Mg/160 Iu, CALCİDAY G 1000 MG/880 IU/50 MG EFERVESAN TABLET, 40 ADETTerbutaline
go.drugbank.com/drugs/DB00871ApprovedInvestigationalTerbutaline was first synthesized in 1966 and described in the literature in the late 1960s and early 1970s. It is a selective beta-2 adrenergic agonist used as a bronchodilator in asthmatic patients. Terbutaline was granted FDA approval...
Mixtures: BİCANA 1,5 MG/5 ML + 66,5 MG/5 ML ŞURUP, 100 ML, BRELAX 1,5 MG+66,5 MG/5 ML ŞURUP, 100 MLCategories: Agents to Treat Airway DiseaseMethotrimeprazine
go.drugbank.com/drugs/DB01403ApprovedA phenothiazine with pharmacological activity similar to that of both chlorpromazine and promethazine.
Synonyms: (-)-(2R)-3-(2-methoxy-10H-phenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine, (-)-10-(3-(Dimethylamino)-2-methylpropyl)-2-methoxyphenothiazineCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Serotonin 5-HT2 Receptor AntagonistsGabapentin
go.drugbank.com/drugs/DB00996ApprovedInvestigationalIt is structurally and functionally related to another GABA derivative, [pregabalin]. … [L8717] It was originally developed as a novel anti-epileptic for the treatment of certain types of seizures[A186277,A186143] - today it is also widely used to treat neuropathic pain.
Mixtures: Cyclo/Gaba 10/300 Pack, Therapentin-60Products: GABATEVA 100 MG KAPSUL, 20 ADET, ROTALEPTIN 100 MG KAPSÜL ,20 KAPSÜLIdarubicin
go.drugbank.com/drugs/DB01177ApprovedInvestigationalAn orally administered anthracycline antineoplastic. The compound has shown activity against breast cancer, lymphomas and leukemias, together with the potential for reduced cardiac toxicity.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesProducts: IDARUB 10 MG IV LIYOFILIZE TOZ IÇEREN FLAKON ,1 ADET, ZAVEDOS CS INJECTION 10 mg/10 mlCobamamide
go.drugbank.com/drugs/DB11191ApprovedNutraceuticalPlease refer to the entry [DB00115] for more information on this entry. … It is therefore important to treat vitamin B12 deficiency with a combination of MeCbl and AdCbl or hydroxocobalamin or cobalamin [L2054].
Synonyms: 5'-Deoxy-5'-adenosylcobalaminProducts: AKTİBOL 1000 MCG LİYOFİLİZE ENJEKSİYONLUK TOZ, 100 ADET, AKTİBOL 1000 MCG LİYOFİLİZE ENJEKSİYONLUK TOZ, 50 ADETFluvoxamine
go.drugbank.com/drugs/DB00176ApprovedInvestigationalAs of the end of 1995, more than 10 million patients worldwide have been treated with fluvoxamine. … Though it is in the same class as other SSRI drugs, it is most often used to treat obsessive-compulsive disorder.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Cytochrome P-450 SubstratesProducts: FAVERIN 100 MG, REVOXIN 100 MG FILM TABLET, 30 ADETSelexipag
go.drugbank.com/drugs/DB11362ApprovedInvestigationalSelexipag was approved by the United States FDA on December 22, 2015 for the treatment of pulmonary arterial hypertension (PAH) to delay disease progression and reduce risk of hospitalization. … Marketed by Actelion Pharmaceuticals under brand name Uptravi, selexipag and its active metabolite, ACT-333679 (MRE-269), act as agonists of the prostacyclin receptor to increase vasodilation in the pulmonary
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: UPTRAVI 1600 MCG FILM KAPLI TABLET, 60 ADET, UPTRAVI 1600 MCG