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Dimethylcurcumin
go.drugbank.com/drugs/DB06133InvestigationalDimethylcurcumin is a synthetic chemical compound that is loosely based on a compound found in curcumin. It is a novel anti-androgen that enhances androgen receptor degradation.
Aminoimidazole carboxamide
go.drugbank.com/drugs/DB06143InvestigationalSynonyms: 5-Aminoimidazol-4-carboxamide, 5-Aminoimidazole-4-carboxamideCategories: Heterocyclic Compounds, 1-RingSertindole
go.drugbank.com/drugs/DB06144ApprovedWithdrawnSertindole, a neuroleptic, is one of the newer antipsychotic medications available. Serdolect is developed by the Danish pharmaceutical company H. Lundbeck. … It is a phenylindole derivative used in the treatment of schizophrenia.
Synonyms: 1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1-piperidyl]ethyl]imidazolidin-2-oneCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingSulfathiazole
go.drugbank.com/drugs/DB06147ApprovedVet approvedWithdrawnSulfathiazole is a short-acting sulfa drug. It used to be a common oral and topical antimicrobial until less toxic alternatives were discovered.
Synonyms: N(1)-2-Thiazolylsulfanilamide, 4-Amino-N-2-thiazolylbenzenesulfonamideCategories: Heterocyclic Compounds, 1-RingMianserin
go.drugbank.com/drugs/DB06148ApprovedWithdrawnA tetracyclic compound with antidepressant effects. Mianserin was previously available internationally, however in most markets it has been phased out in favour of [mirtazapine].
Synonyms: 1,2,3,4,10,14b-Hexahydro-2-methyldibenzo(c,f)pyrazino(1,2-a)azepineCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 3-RingAcetylcysteine
go.drugbank.com/drugs/DB06151ApprovedInvestigational[L31378,L31383,L31388,L31478] Acetylcysteine has also been studied for a wide variety of off-label indications with mixed results.
Synonyms: (R)-2-acetylamino-3-mercaptopropanoic acid, L-α-acetamido-β-mercaptopropionic acidMixtures: N-ACETILCISTEÍNA 2 G + GUAYACOLATO DE GLICERILO 2 G JARABE, AMINOPLASMAL-5% E INFUSIONNylidrin
go.drugbank.com/drugs/DB06152ApprovedWithdrawnNylidrin is a peripheral vasodilator.
Categories: 2-Amino-1-Phenylethanol Derivatives, Cytochrome P-450 SubstratesRimonabant
go.drugbank.com/drugs/DB06155ApprovedInvestigationalWithdrawnThis decision was made after a U.S. advisory panel recommended the medicine not be approved because it may increase suicidal thinking and depression.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingProducts: ACOMPLIA ® COMPRIMIDOS RECUBIERTOS20 MGIstaroxime
go.drugbank.com/drugs/DB06157InvestigationalSynonyms: (E,Z)-Istaroxime, 3-((2-Aminoethoxy)imino)-5alpha-androstan-6,17-dioneGarenoxacin
go.drugbank.com/drugs/DB06160ExperimentalGarenoxacin, a quinolone antibiotic, is being investigated for the treatment of gram-positive and gram-negative bacterial infections.
Categories: 4-Quinolones, Heterocyclic Compounds, 2-Ring