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Zosurabalpin
go.drugbank.com/drugs/DB21539InvestigationalZosurabalpin is under investigation in clinical trial NCT05614895 (A Study to Investigate the Pharmacokinetics of RO7223280 in Critically Ill Participants With Bacterial Infections).
Sodium sulfide
go.drugbank.com/drugs/DB11159ApprovedInterestingly, sodium sulfide was shown to have some cardioprotective role against cardiac ischemia or reperfusion injury, as well as protect lungs against ventilator-induced lung injury [A27275].
Lumiliximab
go.drugbank.com/drugs/DB06162InvestigationalResults published from the CLL clinical trial failed to meet primary endpoints.
Trodusquemine
go.drugbank.com/drugs/DB06333InvestigationalIt has demonstrated the ability to stimulate regeneration of heart and multiple other tissues in animal models [A176600].
AAV-AIPL
go.drugbank.com/drugs/DB17857ExperimentalDeveloped by MeiraGTx, it is being investigated for the treatment of inherited retinal dystrophy due to defects in _AIPL1_ gene.
Elsibucol
go.drugbank.com/drugs/DB05840ExperimentalAGI-1096 is a novel oral antioxidant and selective anti-inflammatory agent that is being developed to address the accelerated inflammation of grafted blood vessels, known as transplant arteritis, common
Olinciguat
go.drugbank.com/drugs/DB15238InvestigationalOlinciguat is under investigation in clinical trial NCT03892499 (A Trial to Evaluate the Effect of Itraconazole (ITZ), a CYP3A4 Inhibitor, on the Pharmacokinetics of the Soluble Guanylate Cyclase Stimulator
Mezigdomide
go.drugbank.com/drugs/DB17584InvestigationalMezigdomide is under investigation in clinical trial NCT05372354 (A Study to Evaluate Safety, Drug Levels and Effectiveness of CC-92480 (BMS-986348) in Combination With Other Treatments in Participants
RGX-111
go.drugbank.com/drugs/DB17632InvestigationalRGX-111 is an adeno-associated virus vector AAV9 designed to deliver the α-L-iduronidase (IDUA) gene.