Search
Atracurium
go.drugbank.com/drugs/DB13295ApprovedInvestigationalWithdrawnCategories: Heterocyclic Compounds, 2-RingProducts: TRACRİUM 25 MG/2.5 ML ENJEKSİYONLUK/İNFÜZYONLUK ÇÖZELTİ, 5 ADET, DEMATRAC 25 MG/2.5 ML IV İNFÜZYON İÇİN SOLÜSYON İÇEREN AMPUL, 10 AMPULTocilizumab
go.drugbank.com/drugs/DB06273ApprovedInvestigationalTocilizumab is a recombinant humanized monoclonal antibody IL-6 receptor inhibitor used to treat inflammatory and autoimmune conditions. … [L12789] It was first described in the literature in 2003 when Chugai, a subsidiary of Roche began developing IL-6 inhibiting monoclonal antibodies.
Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 InducersProducts: ACTEMRA 400 MG/20 ML IV INFUZYONLUK COZELTI KONSANTRESI İÇEREN FLAKON, 1 ADET, ACTEMRA 400 MG/20 ML IV INFUZYONLUK COZELTI KONSANTRESI İÇEREN FLAKON, 4 ADETAntithymocyte immunoglobulin (rabbit)
go.drugbank.com/drugs/DB00098ApprovedInvestigationalThymoglobulin is a mixture of antibodies intended to bind to various cell surface antigens. The most common mode of action of Thymoglobulin is via selective depletion of T-cells. … Thymoglobulin is a polyclonal antibody that suppresses certain types of immune cells responsible for acute organ rejection in transplant patients.
Categories: Immunoglobulin G, Increased T Lymphocyte DestructionSynonyms: r-ATG, Lapine T-lymphocyte immune globulinColchicine
go.drugbank.com/drugs/DB01394ApprovedInvestigationalColchicine is an alkaloid drug derived from a plant belonging to the Lily family, known as _Colchicum autumnale_, or "autumn crocus."[A183611] Its use was first approved by the FDA in 1961.
Categories: P-glycoprotein inducers, P-glycoprotein substratesProducts: Colctab 1 mg Tabletten, Colchanova 1 mg TablettenClobazam
go.drugbank.com/drugs/DB00349ApprovedIllicitInvestigational[A256963,A256868] This is likely because of clobazam's higher affinity to the α<sub>2</sub> subunit of the GABA<sub>A</sub> receptor, which mediates anxiolytic effects, than the α<sub>1</sub> subunit, … [A256868] Additionally, clobazam is believed to be a partial agonist to the GABA<sub>A</sub> receptor rather than non-selective full receptor agonists like 1,4-benzodiazepines, thus potentially explaining
Synonyms: 7-Chloro-1-methyl-5-phenyl-1,5-dihydro-benzo[b][1,4]diazepine-2,4-dione, 1-phenyl-5-methyl-8-chloro-1,2,4,5-tetrahydro-2,4-dioxo-3H-1,5-benzodiazepineCategories: Heterocyclic Compounds, 2-Ring, GABA-A Receptor AgonistsDoxofylline
go.drugbank.com/drugs/DB09273InvestigationalIn contrast with other xanthine derivatives, doxofylline does not significantly bind to adenosine alpha-1 or alpha-2 receptors and lacks stimulating effects. … Doxofylline is a methylxanthine derivative with the presence of a dioxolane group in position 7.
Mixtures: MUCOFIX 600/200 MG EFERVESAN, 20 ADET, MUCOFIX 900/400 MG EFERVESAN TABLET, 20 ADETCategories: Adrenergic beta-2 Receptor Agonists, Heterocyclic Compounds, 2-RingPamidronic acid
go.drugbank.com/drugs/DB00282ApprovedInvestigationalPamidronic acid is a second generation, nitrogen containing bisphosphonate similar to [neridronic acid] and [alendronic acid].[A203111] Pamidronic acid was first described in the literature in 1977.
Products: Pamidronate Disodium Omega 6 mg/ml, Pamidronate Disodium Omega 9 mg/mlCetirizine
go.drugbank.com/drugs/DB00341ApprovedInvestigationalOne of the most common uses for this drug is for a condition called _allergic rhinitis_.
Mixtures: ACERADOX® G, ZYRTEC D 12 HourCategories: P-glycoprotein inhibitors, P-glycoprotein substratesCarnitine O-palmitoyltransferase 2, mitochondrial
go.drugbank.com/bio_entities/BE0000179TargetHumansInvolved in the intramitochondrial synthesis of acylcarnitines from accumulated acyl-CoA metabolites (PubMed:20538056, PubMed:24780397). Reconverts acylcarnitines back into the respective acyl-CoA esters that can then undergo beta-oxidat...
Polypeptides: Carnitine O-palmitoyltransferase 2, mitochondrialProstaglandin G/H synthase 2
go.drugbank.com/bio_entities/BE0000262TargetEnzymeHumansMetabolizes 2-arachidonoyl glycerol yielding the glyceryl ester of PGH2, a process that can contribute to pain response (PubMed:22942274). … In an alternative pathway of prostanoid biosynthesis, converts 2-arachidonoyl lysophospholipids to prostanoid lysophospholipids, which are then hydrolyzed by intracellular phospholipases to release free
Polypeptides: Prostaglandin G/H synthase 2Synonyms: COX-2, PGHS-2