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Displaying results 4871 - 4880 of 10000 in total
  1. Drug

    Paroxetine

    go.drugbank.com/drugs/DB00715
    ApprovedInvestigational

    Paroxetine is a selective serotonin reuptake inhibitor (SSRI) drug commonly known as Paxil. … Paroxetine is well tolerated in most patients with a similar adverse effect profile to other members of its drug class.

    Synonyms: (3S-trans)-3-((1,3-benzodioxol-5-yloxy)methyl)-4-(4-fluorophenyl)piperidine, (−)-(3S,4R)-4-(p-fluorophenyl)-3-((3,4-(methylenedioxy)phenoxy)methyl)piperidineCategories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates
  2. Target

    Uncharacterized MFS-type transporter EfpA

    go.drugbank.com/bio_entities/BE0009715
    TargetMycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

    Synonyms: Efflux protein A
  3. Indication

    Fever

    go.drugbank.com/conditions/DBCOND0020923
    Drugs: Acetaminophen · Acetylsalicylic acid · Ascorbic acid · Brompheniramine · Caffeine · Chlorpheniramine +20 more
    Synonyms: Has a temperature
  4. Drug

    Sultamicillin

    go.drugbank.com/drugs/DB12127
    ApprovedWithdrawn

    Sultamicillin has been used in trials studying the prevention and treatment of Ventilator Associated Pneumonia and Chronic Obstructive Pulmonary Disease (COPD).

    Categories: Penicillin G, Heterocyclic Compounds, 2-RingProducts: TYCLAR® 250MG/5ML POLVO PARA RECONSTITUIR A SUSPENSIÓN ORAL., BACTESUL 1 G/ 5 ML
  5. Drug

    Valaciclovir

    go.drugbank.com/drugs/DB00577
    ApprovedInvestigational

    Valacyclovir is the L-valine ester of aciclovir. It is a member of the purine (guanine) nucleoside analog drug class [F3949]. … Genital herpes is a frequently diagnosed sexually transmitted disease which currently affects more than 400 million individuals worldwide.

    Categories: Heterocyclic Compounds, 2-RingSynonyms: L-Valine, 2-((2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy)ethyl ester, L-Valine ester with 9-((2-hydroxyethoxy)methyl)guanine
  6. Drug

    Zopiclone

    go.drugbank.com/drugs/DB01198
    ApprovedInvestigational

    Zopiclone is a novel hypnotic agent used in the treatment of insomnia. Its mechanism of action is based on modulating benzodiazepine receptors.

    Synonyms: 6-(5-Chloro-2-pyridinyl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl 4-methyl-1-piperazinecarboxylateCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-Ring
  7. Indication

    Febrile Illness Acute

    go.drugbank.com/conditions/DBCOND0059951
    Drugs: Acetaminophen
    Synonyms: Has a temperature
  8. Drug

    Metronidazole

    go.drugbank.com/drugs/DB00916
    ApprovedInvestigational

    a wide variety of infections. … Metronidazole is a commonly used antibiotic, belonging to the nitroimidazole class of antibiotics.

    Synonyms: 1-(2-hydroxy-1-ethyl)-2-methyl-5-nitroimidazole, 1-(β-ethylol)-2-methyl-5-nitro-3-azapyrroleInternational brands: Tricowas B
  9. Pathway

    Vitamin A Deficiency

    smpdb.ca/view/SMP0125788
    Disease

    Vitamin A deficiency can be caused by many causes. A defect in the BCMO1 gene which codes for beta,beta-carotene 15,15’-monooxygenase is one of them. … A defect in this enzyme results in decrease of levels of retinal and vitamin A in serum; Signs and symptoms include night blindness, poor adaptation to darkness, dry skin and hair.

    Drugs: NADH · Vitamin A · Alitretinoin · Tretinoin · Iron · Zinc +2 more
  10. Drug

    Ursodeoxycholic acid

    go.drugbank.com/drugs/DB01586
    ApprovedInvestigational

    Ursodeoxycholic acid (UDCA), also known as ursodiol, is a naturally-occurring bile acid that constitutes a minor fraction of the human bile acid pool. … [A256272,A256277] UDCA has been used to treat liver disease for decades: its first use in traditional medicine dates back more than a hundred years.

    Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 Enzyme InducersProducts: ACIDO URSODESOSSICOLICO EG, ACIDO URSODESOSSICOLICO EG STADA