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Cetrorelix
go.drugbank.com/drugs/DB00050ApprovedInvestigationalCetrorelix is a man-made hormone that blocks the effects of Gonadotropin Releasing Hormone (GnRH). … GnRH controls another hormone that is called luteinizing hormone (LH), which is the hormone that starts ovulation during the menstrual cycle.
Products: CETROTIDE® 0.25MG, CETROTIDE 3 MG.Ixabepilone
go.drugbank.com/drugs/DB04845ApprovedInvestigationalIxabepilone is an epothilone B analog developed by Bristol-Myers Squibb as a cancer drug. … Ixabepilone is administered through injection, and will be marketed under the trade name Ixempra. Ixabepilone is a semisynthetic analogue of epothilone B.
Synonyms: Azaepothilone B, Aza-epothilone BCategories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index2,2':6',2''-Terpyridine Platinum(Ii)
go.drugbank.com/drugs/DB01912Experimental2,2':6',2''-terpyridine Platinum(Ii) is a solid. Known drug targets of 2,2':6',2''-Terpyridine Platinum(Ii) include truncated transposase and autolysin.
Synonyms: 2,2':6',2''-Terpyridine Platinum(Ii)Veltuzumab
go.drugbank.com/drugs/DB05656InvestigationalVeltuzumab is a monoclonal antibody which, as of October 2009, is undergoing Phase I/II clinical trials for the treatment of non-Hodgkin's lymphoma.
Physostigmine
go.drugbank.com/drugs/DB00981ApprovedA cholinesterase inhibitor that is rapidly absorbed through membranes. It can be applied topically to the conjunctiva. … It also can cross the blood-brain barrier and is used when central nervous system effects are desired, as in the treatment of severe anticholinergic toxicity.
Categories: Heterocyclic Compounds, 2-RingGliquidone
go.drugbank.com/drugs/DB01251ApprovedGliquidone is a sulfonylurea drug used to treat diabetes mellitus type 2. It is an ATP-dependent K+ (KATP) channel blocker. … This block causes a depolarization which leads to activation of voltage-dependent Ca channels and Ca2+ influx, and eventually increases insulin release.
International brands: Jie ShiCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesFlunarizine
go.drugbank.com/drugs/DB04841ApprovedInvestigationalFlunarizine is a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity. … It is effective in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and peripheral origin, and as an adjuvant in the therapy of epilepsy.
Synonyms: 1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenylprop-2-en-1-yl]piperazineCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingFusidic acid
go.drugbank.com/drugs/DB02703ApprovedInvestigationalIt is often used topically in creams and eyedrops but is available in systemic formulations including tablets and injections.
Mixtures: FUCICORT(R), FUCIDIN H %2 + %1 KREM, 30 GCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 InhibitorsSR-9011
go.drugbank.com/drugs/DB14014ExperimentalSR-9011 is a REV-ERB agonist. … SR-9011 has been demonstrated that it is specifically lethal to cancer cells and oncogene-induced senescent cells, including melanocytic naevi, and has no effect on the viability of normal cells or tissues
Synonyms: 1-Pyrrolidinecarboxamide, 3-((((4-chlorophenyl)methyl)((5-nitro-2-thienyl)methyl)amino)methyl)-n-pentyl-Categories: Heterocyclic Compounds, 1-RingLanolin alcohols
go.drugbank.com/drugs/DB14181ApprovedLanolin alcohols are a complex combination of organic alcohols obtained by the hydrolysis of lanolin. … It is administered as an ointment base with topical insulin and has shown to be antagonistic to wound healing. It is commonly used in allergenic testing.