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Typhoid Vaccine Live
go.drugbank.com/drugs/DB11050ApprovedInvestigationalThe vaccine prevents the development of typhoid fever, an acute, febrile enteric disease caused by *Salmonella typhi* by inducing a local immune response in the intestinal tract. … Salmonella typhi Ty21a live antigen is a live attenuated vaccine for oral administration only. It contains the attenuated strain *Salmonella typhi* Ty21a.
Products: Vivotif 2 x 10^9 - 2 x 10^10 CFU magensaftresistente Hartkapsel, Vivotif LRGX-121
go.drugbank.com/drugs/DB17681InvestigationalRGX-121 is designed to use the NAV AAV9 vector to deliver the human iduronate-2-sulfatase gene to the central nervous system.
Synonyms: Non-replicating recombinant adeno-associated virus (AAV) vector of serotype 9 expressing human iduronate-2-sulfataseLabetuzumab
go.drugbank.com/drugs/DB05097InvestigationalLabetuzumab is a humanized monoclonal antibody to carcinoembryonic antigen that inhibits tumor growth. It is used in radioimmunotherapy.
Synonyms: MN14 monoclonal antibody to carcinoembryonic antigenMPI-674
go.drugbank.com/drugs/DB05749ExperimentalAIs are a class of drugs that reduce the amount of estrogen circulating in the body by binding to and inhibiting the enzyme aromatase, which is responsible for converting certain hormones to estrogen. … It is developed for the treatment of several serious women’s health conditions including endometrial thinning prior to endometrial ablations in premenopausal women with abnormal uterine bleeding (AUB).
NOV-002
go.drugbank.com/drugs/DB05393InvestigationalNOV-002, the lead compound acts as a chemoprotectant and an immunomodulator, in combination with chemotherapy. … NOV-002 is approved and marketed in the Russian Fereration by Pharma BAM under the trade name Glutoxim.
Epofolate
go.drugbank.com/drugs/DB12266InvestigationalEpofolate (BMS-753493) is a folate conjugate of the epothilone analog BMS-748285 that was designed to selectively target folate receptor expressing cancer cells. … and neutropenia appear to have been less frequent and less severe as compared to epothilones.
Categories: Cytochrome P-450 CYP3A Inhibitors, Heterocyclic Compounds, 2-RingCefapirin
go.drugbank.com/drugs/DB01139ApprovedVet approvedCefapirin (INN, also spelled cephapirin), commonly marketed under the trade name Cefadyl, is a first-generation cephalosporin antibiotic that is available in injectable formulations. … Production for use in humans has been discontinued in the United States. Cefapirin is partly plasma-bound and is effective against gram-negative and gram-positive organisms.
Categories: Heterocyclic Compounds, 2-RingSynonyms: (6R,7R)-3-(acetoxymethyl)-8-oxo-7-{[(pyridin-4-ylsulfanyl)acetyl]amino}-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acidEzogabine
go.drugbank.com/drugs/DB04953ApprovedWithdrawnEzogabine (D23129) is a close structural analog of the centrally acting analgesic flupitrine. … FDA approved in June 10, 2011 under the name of ezogabine.
Synonyms: N-(2-Amino-4-(4-fluorobenzylamino)-phenyl) carbamic acid ethyl ester, ethyl {2-amino-4-[(4-fluorobenzyl)amino]phenyl}carbamateDiaminopyrimidine oxide
go.drugbank.com/drugs/DB18756ApprovedDiaminopyrimidine oxide is a compound similar to [minoxidil] which is used to aid in hair growth.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 2,4-diaminopyrimidine 3-n-oxide, 2,4-pyrimidinediamine, 3-oxidePZM21
go.drugbank.com/drugs/DB14030ExperimentalPZM21 is a novel μ-opioid receptor (MOPr) ligand that has been reported to induce minimal arrestin recruitment and be devoid of the respiratory depressant effects characteristic of classical μ-opioid ligands … such as morphine.