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Levocetirizine
go.drugbank.com/drugs/DB06282ApprovedInvestigationalLevocetirizine is a selective histamine H<sub>1</sub> antagonist used to treat a variety of allergic symptoms.[A181748,A181790,L7694] It is the R enantiomer of [cetirizine]. … [L7694] Levocetirizine has greater affinity for the histamine H<sub>1</sub> receptor than cetirizine.[L7694] Levocetirizine was granted FDA approval in 1995.[L7694]
Synonyms: 2-(2-{4-[(R)-(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acidMixtures: NORAVER ® GFAST CAPSULAS BLANDAS CONTRA LOS SINTOMAS DE LA GRIPA, BREATHEZY - LAlfacalcidol
go.drugbank.com/drugs/DB01436ApprovedInvestigationalNutraceuticalAlfacalcidol, or 1-alpha-hydroxycholecalciferol or 1-alpha-hydroxyvitamin D3, is a non-endogenous analogue of [vitamin D]. … The pharmacological actions of alfacalcidol are prolonged than vitamin D because a negative feedback mechanism regulates the final activation step of vitamin D in the kidneys.
Synonyms: (5Z,7E)-9,10-seco-5,7,10(19)-cholestatrien-1α,3β-diol, 9,10-secocholesta-5,7,10(19)-triene-1α,3β-diolCategories: Drugs for Treatment of Bone DiseasesSalmon calcitonin
go.drugbank.com/drugs/DB00017ApprovedInvestigationalSynthetic peptide, 32 residues long formulated as a nasal spray.
Products: แคลซิ - 10, Pro-calcitonin - 200Vigabatrin
go.drugbank.com/drugs/DB01080ApprovedInvestigational[A202124] Its use is now generally reserved for patients who have failed alternative therapies, and its US approval by the FDA in 2009 mandated the creation of a drug registry to monitor patients for visual … Although administered as a racemic mixture, only the S(+) enantiomer is pharmacologically active.
Products: Sabril Pwr 1g/sachet, SABRIL 500 MG 50 SASEIdarubicin
go.drugbank.com/drugs/DB01177ApprovedInvestigationalThe compound has shown activity against breast cancer, lymphomas and leukemias, together with the potential for reduced cardiac toxicity.
Categories: Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic IndexSynonyms: (1S,3S)-3-acetyl-3,5,12-trihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydronaphthacen-1-yl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosideAsfotase alfa
go.drugbank.com/drugs/DB09105ApprovedInvestigationalAsfotase alfa is a first-in-class bone-targeted enzyme replacement therapy designed to address the underlying cause of hypophosphatasia (HPP)—deficient alkaline phosphatase (ALP).
Products: STRENSİQ 40 MG/1.0 ML ENJEKSİYONLUK ÇÖZELTİ, 12 ADET, STRENSİQ 18 MG/0.45 ML ENJEKSİYONLUK ÇÖZELTİ, 12 ADETTigecycline
go.drugbank.com/drugs/DB00560ApprovedInvestigationalFood and Drug Administration (FDA) on June 17, 2005. … Tigecycline is a glycylcycline antibiotic developed and marketed by Wyeth under the brand name Tygacil.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: TIGECYCLINE SANDOZ POWDER FOR SOLUTION FOR INFUSION 50 MG PER VIAL, TIGEVITAE® 50 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLEAcitretin
go.drugbank.com/drugs/DB00459ApprovedInvestigationalIt is the major metabolite of etretinate with the advantage of a much shorter half-life when compared with etretinate.
Categories: Antipsoriatics for Systemic Use, Retinoids for Treatment of PsoriasisProducts: Keracutan 10 mg Kapseln, NEOTIGASON CAPSULE 10 mgCarboxymethylcellulose
go.drugbank.com/drugs/DB11059ApprovedInvestigationalIt is added in food products as a viscosity modifier or thickener and emulsifier. … Carboxymethylcellulose is a cellulose derivative that consists of the cellulose backbone made up of glucopyranose monomers and their hydroxyl groups bound to carboxymethyl groups.
Mixtures: Clear Eyes for Dry EyesCategories: Compounds used in a research, industrial, or household settingClobazam
go.drugbank.com/drugs/DB00349ApprovedIllicitInvestigational[A256963,A256868] This is likely because of clobazam's higher affinity to the α<sub>2</sub> subunit of the GABA<sub>A</sub> receptor, which mediates anxiolytic effects, than the α<sub>1</sub> subunit, … [A256868] Additionally, clobazam is believed to be a partial agonist to the GABA<sub>A</sub> receptor rather than non-selective full receptor agonists like 1,4-benzodiazepines, thus potentially explaining
Synonyms: 7-Chloro-1-methyl-5-phenyl-1,5-dihydro-benzo[b][1,4]diazepine-2,4-dione, 1-phenyl-5-methyl-8-chloro-1,2,4,5-tetrahydro-2,4-dioxo-3H-1,5-benzodiazepineCategories: GABA-A Receptor Agonists