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Choline
go.drugbank.com/drugs/DB00122ApprovedInvestigationalNutraceuticalIt is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism. … A basic constituent of lecithin that is found in many plants and animal organs.
Mixtures: Doctor's Choice Brand for Men, Daily Energy Brand B-complexMethylphenidate
go.drugbank.com/drugs/DB00422ApprovedInvestigational[A177541] There is a dose-related effect of psychostimulants on receptor stimulation, where higher doses are shown to increase norepinephrine (NE) and dopamine (DA) efflux throughout the brain which can … In contrast, low doses are found to selectively activate NE and DA neurotransmission within the prefrontal cortex which is an area of the brain thought to play a prominent role in ADHD pathophysiology,
Products: RITALINA® LA 20 MG CAPSULAS DE LIBERACION PROLONGADA, Ritalin LAIrinotecan
go.drugbank.com/drugs/DB00762ApprovedInvestigational[L50181, L50186, L50201] Irinotecan liposome was approved by the FDA in February 2024.[L50186] The active metabolite SN-38 is also a potent inhibitor of DNA topoisomerase I. … Both irinotecan and SN-38 mediate antitumor activity by forming a complex with topoisomerase I and blocking its enzymatic activity, thereby interfering with DNA synthesis.
Categories: UGT1A1 Substrates with a Narrow Therapeutic Index, UGT1A9 Substrates with a Narrow Therapeutic IndexProducts: DARITEX-A, CLORHIDRATO DE IRINOTECAN TRIHIDRATO 20 MG/MLLosartan
go.drugbank.com/drugs/DB00678ApprovedInvestigational[L7423] Angiotensin-converting enzyme (ACE) inhibitors are used for a similar indication but are associated with a cough. … [L7423] Losartan was granted FDA approval on 14 April 1995.[L7423]
Mixtures: Hyzaar DS, SARAVANTA-DProducts: LOSARTAN DR. REDDY'S, LOSARTAN 25 1A PHARMAGranisetron
go.drugbank.com/drugs/DB00889ApprovedInvestigationalA serotonin receptor (5HT-3 selective) antagonist that has been used as an antiemetic and antinauseant for cancer chemotherapy patients.
Products: GRANI-DENK 1 MG/ ML- AMPOLLA DE 1 ML, GRANISETRON MYLAN GENERICSBenazepril
go.drugbank.com/drugs/DB00542ApprovedInvestigationalBenazepril, brand name Lotensin, is a medication used to treat high blood pressure (hypertension), congestive heart failure, and chronic renal failure[A838,A837]. … Upon cleavage of its ester group by the liver, benazepril is converted into its active form benazeprilat, a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor[A836].
Mixtures: BENAZEPRIL 1A COM 20/25MG, BENAZEPRIL 1A COM10/12.5MGProducts: BENAZEPRIL 1A PHARMA 5MG, BENAZEPRIL 1A PHARMA 10MGDesogestrel
go.drugbank.com/drugs/DB00304ApprovedInvestigationalDesogestrel, a prodrug, is a third generation progestogen[A176315] and hence, a member of the gonane family which was largely used in Europe before being approved in the US and Canada. … [A176342] The first approved drug containing desogestrel was developed by Organon USA Inc in 1972 and FDA approved in 1992.[L5762]
Mixtures: Apri 28 Day, Apri 28 DayImatinib
go.drugbank.com/drugs/DB00619ApprovedInvestigational[A249305] It was deemed a "miracle drug" due to its clinical success, as oncologist Dr. … [L42220] Imatinib was approved on February 1st ,2001 by the FDA and November 7th, 2001 by the EMA; however, its European approval has been withdrawn in October 2023.[A263036,L49746,L49751]
Products: IMATINIB DR. REDDY'S, IMATINIB 1A PHARMA 100MGOrnidazole
go.drugbank.com/drugs/DB13026InvestigationalOrnidazole has been used in trials studying the prevention of Elective Colorectal Surgery.
Products: TIBERAL ROCHE DE 500 MG