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Zonisamide
go.drugbank.com/drugs/DB00909ApprovedInvestigationalThe US and Europe approved it in 2000 and 2005, respectively.[A1379,A1383] … [L42530,L42535] Zonisamide represents an alternative for patients that remain refractory to established antiepileptic drugs. In 1989, it was approved for commercial use in Japan.
Categories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 SubstratesProducts: ZONISAHEXAL 50 MG HKP, Zonibon 50 mg-HartkapselnPeginterferon alfa-2b
go.drugbank.com/drugs/DB00022ApprovedInvestigationalPeginterferon alfa-2b is a form of recombinant interferon used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). … Treatment options for chronic Hepatitis C have advanced significantly since 2011, with the development of Direct Acting Antivirals (DAAs) resulting in less use of Peginterferon alfa-2b.
Categories: peginterferon alfa-2b, peginterferon alfa-2b, combinationsSynonyms: PEG-IFN-α-2b, Peg interferon alfa-2bCarbocisteine
go.drugbank.com/drugs/DB04339ApprovedInvestigationalCarbocisteine is a mucolytic drug that alleviates respiratory symptoms and infections by reducing the viscosity of mucus, allowing it to be expelled. … reported by physicians in France and Italy.
Synonyms: (L)-2-Amino-3-(carboxymethylthio)propionic acidProducts: MUCOSIS 50 MG/ML ŞURUP, 100 ML, SCMC SYRUP 100 100 mg/5 mlAlbendazole
go.drugbank.com/drugs/DB00518ApprovedInvestigationalVet approved(From Martindale, The Extra Pharmacopoeia, 30th ed, p38)
Categories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 SubstratesSynonyms: O-methyl N-(5-(propylthio)-2-benzimidazolyl)carbamate, 5-(propylthio)-2-carbomethoxyaminobenzimidazoleAripiprazole
go.drugbank.com/drugs/DB01238ApprovedInvestigational[L45859] It is also indicated as an injection for agitation associated with schizophrenia or bipolar mania. … [L45859] Aripiprazole exerts its effects through agonism of dopaminergic and 5-HT1A receptors and antagonism of alpha-adrenergic and 5-HT2A receptors.
Categories: Heterocyclic Compounds, 2-Ring, Serotonin 5-HT1 Receptor AgonistsProducts: ARIPIPRAZOLO EG, ARIP MT 10 TABLETS 10mgDolutegravir
go.drugbank.com/drugs/DB08930ApprovedInvestigational[A7514] The effect of this drug has no homology in human host cells, which gives it excellent tolerability and minimal toxicity. … [L1035] On November 21, 2017, dolutegravir, in combination with rilpivirine, was approved as part of the first complete treatment regimen with only two drugs for the treatment of adults with HIV-1 named
Mixtures: TRIUMEQ® 50 MG / 600 MG / 300 MG, TRIUMEQ 50 MG/600 MG/300 MG FILM KAPLI TABLET,90 FILM KAPLI TABLETCategories: Antivirals used in combination for the treatment of HIV infectionsMicafungin
go.drugbank.com/drugs/DB01141ApprovedInvestigationalIt belongs to the antifungal class of compounds known as echinocandins and exerts its effect by inhibiting the synthesis of 1,3-beta-D-glucan, an integral component of the fungal cell wall. … Micafungin is an antifungal drug.
Products: Micafungin Hikma 100 mg Pulver für ein Konzentrat zur Herstellung einer Infusionslösung, Micafungin Biocon 100 mg Pulver für ein Konzentrat zur Herstellung einer InfusionslösungEpirubicin
go.drugbank.com/drugs/DB00445ApprovedInvestigationalAn anthracycline which is the 4'-epi-isomer of doxorubicin. The compound exerts its antitumor effects by interference with the synthesis and function of DNA.
Synonyms: (1S,3S)-3-GLYCOLOYL-1,2,3,4,6,11-HEXAHYDRO-3,5,12-TRIHYDROXY-10-METHOXY-6,11-DIOXO-1-NAPHTHACENYL 3-AMINO-2,3,6-TRIDEOXY-.ALPHA.-L-ARABINO-HEXOPYRANOSIDE, 5,12-NAPHTHACENEDIONE, 10-((3-AMINO-2,3,6-TRIDEOXY-.ALPHA.-L-ARABINO-HEXOPYRANOSYL)OXY)-7,8,9,10-TETRAHYDRO-6,8,11-TRIHYDROXY-8-(HYDROXYACETYL)-1-METHOXY-, (8S-CIS)-Products: PHARMORUBICIN CS INJECTION 10 mg/5 ml, FARMORUBICINA®SOLUCION INYECTABLE 50 MG/ 25 ML.Gabapentin
go.drugbank.com/drugs/DB00996ApprovedInvestigationalGabapentin is a structural analogue of the inhibitory neurotransmitter gamma-aminobutyric acid ([GABA]) that was first approved for use in the United States in 1993. … unlikely to participate in pharmacokinetic drug interactions.
Mixtures: Cyclo/Gaba 10/300 Pack, GAVINDO NProducts: GABAPENTIN EG, GABATEVA 100 MG KAPSUL, 20 ADETDesloratadine
go.drugbank.com/drugs/DB00967ApprovedInvestigationalIt is the active descarboethoxy metabolite of loratidine (a second generation histamine). … Desloratidine has a long-lasting effect and does not cause drowsiness because it does not readily enter the central nervous system.
Mixtures: DELOFED MR 2.5/120 MG KAPSUL, 20 ADET, DELODAY PLUS 120 MG/2,5 MG EFERVESAN TABLET, 20 ADETSynonyms: 8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine, 8-chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo(5,6)cyclohepta(1,2-b)pyridine