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Displaying results 4991 - 5000 of 10000 in total
  1. Drug

    Digoxin

    go.drugbank.com/drugs/DB00390
    ApprovedInvestigational

    [A178225] It is a common agent used to manage atrial fibrillation and the symptoms of heart failure. … [A178234] Digoxin is classified as a cardiac glycoside and was initially approved by the FDA in 1954.

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, P-glycoprotein inducersInternational brands: Digocard-G
  2. Drug

    Repaglinide

    go.drugbank.com/drugs/DB00912
    ApprovedInvestigational

    Repaglinide metabolites do not possess appreciable hypoglycemic activity. Approximately 90% of a single orally administered dose is eliminated in feces and 8% in urine. … Meglitnides may have a neutral effect on weight or cause a slight increase in weight.

    Mixtures: PAREGLIN 2 MG/500 MG FILM KAPLI TABLET, 90 ADET, REPAMEF 2/500 MG EFERVESAN TABLET, 30 ADETCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-Ring
  3. Drug

    Cyanocobalamin

    go.drugbank.com/drugs/DB00115
    ApprovedInvestigationalNutraceutical

    Cyanocobalamin (commonly known as Vitamin B12) is a highly complex, essential vitamin, owing its name to the fact that it contains the mineral, cobalt.

    Mixtures: Vege Swiss One Multivitamin W Chel Mins Tab, Vitamine Du Groupe B Plus Fer - LiqCategories: Vitamin B 12, biosynthesis, Vitamin B Complex
  4. Drug

    Coagulation factor VIIa Recombinant Human

    go.drugbank.com/drugs/DB00036
    ApprovedInvestigational

    NovoSeven is a vitamin K-dependent glycoprotein consisting of 406 amino acid residues. Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form.

    Categories: Increased Coagulation Factor X ActivityProducts: NOVOSEVEN® RT 2 MG, NOVOSEVENRT 5 MG
  5. Drug

    Prednisolone

    go.drugbank.com/drugs/DB00860
    ApprovedInvestigationalVet approved

    Prednisolone is a glucocorticoid similar to [cortisol] used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects. … [A187463] Prednisolone was granted FDA approval on 21 June 1955.[L9431]

    Synonyms: Predniso(lo)ne, delta(1)-HydrocortisoneInternational brands: Di-Adreson F, Di-Adreson-F
  6. Drug

    Cavrotolimod

    go.drugbank.com/drugs/DB18216
    Investigational

    Synonyms: DNA, D(P-THIO)(T-C-G-T-C-G-T-T-T-T-G-T-C-G-T-T-T-T-G-T-C-G-T-T), 3'-(58-((3.BETA.), -CHOLEST-5-EN-3-YLOXY)-19,39,42-TRIHYDROXY-19,39-DIOXIDO-58-OXO-3,6,9,12,15,18,20,23,26,29,32,35,38,40,44,47,50,53-OCTADECAOXA-57-AZA-19,39-DIPHOSPHAOCTAPENTACONT-1-YL HYDR
  7. Drug

    Hydromorphone

    go.drugbank.com/drugs/DB00327
    ApprovedIllicitInvestigational

    Due to these modifications, it presents a very high potency and comparable side effect profile to the parent compound. … Structurally, hydromorphone derived from [morphine] in the modification of the hydroxyl group in the carbon 6 to a carbonyl and the absence of a double bond between the carbon 7 and 8.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesSynonyms: (-)-(5R)-4,5-Epoxy-3-hydroxy-9α-methylmorphinan-6-one, 6-Deoxy-7,8-dihydro-6-oxomorphine
  8. Drug

    Triamcinolone

    go.drugbank.com/drugs/DB00620
    ApprovedInvestigationalVet approved

    [L8255] Triamcinolone can be used as a one time adjunct treatment of osteoarthritic knee pain,[L8264] or first line as a topical treatment of corticosteroid responsive dermatoses. … [L8246,L8249,L8252,L8255,L8258,L8261,L8264] Triamcinolone was granted FDA approval on 3 December 1957.

    Synonyms: 9-fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione, 11β,16α,17α,21-tetrahydroxy-9α-fluoro-1,4-pregnadiene-3,20-dioneInternational brands: Omcilon-A
  9. Drug

    Azithromycin

    go.drugbank.com/drugs/DB00207
    ApprovedInvestigational

    Azithromycin [9-deoxo-9a-aza-9a-methyl-9a-homoerythromycin] is a part of the _azalide_ subclass of macrolides, and contains a 15-membered ring, with a methyl-substituted nitrogen instead of a carbonyl … Azithromycin is a broad-spectrum macrolide antibiotic with a long half-life and a high degree of tissue penetration [A174172]. It was initially approved by the FDA in 1991 [A174175].

    Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: MENAZİD-L 500 MG IV ENJEKSİYONLUK LİYOFİLİZE TOZ İÇEREN FLAKON, 1 ADET, AZİTROTEK 500 MG FİLM TABLET, 2 TABLET
  10. Drug

    Somatotropin

    go.drugbank.com/drugs/DB00052
    ApprovedInvestigational

    [A228183, L31508] Synthesized in a strain of _Escherichia coli_, recombinant HGH is a polypeptide hormone that contains 191 amino acid residues with a molecular weight of 22 kDa. … [A228188] Recombinant growth hormone is available as a subcutaneous injection for children and adults under a wide variety of brand names.

    Mixtures: Nutropin - Kit Pws(5mg) & Liq(10ml) Im ScCategories: P-glycoprotein substrates, Cytochrome P-450 CYP1A2 Inducers