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Displaying results 5011 - 5020 of 10000 in total
  1. Drug

    Teglarinad chloride

    go.drugbank.com/drugs/DB05217
    Investigational

    In vivo, apoptosis inducer GMX1777 is rapidly converted into GMX1778 through hydrolytic cleavage of a carbonate ester bond. … Although the exact mechanism of action has yet to be fully elucidated, GMX1778 appears to antagonize nuclear factor-kappa B (NF-kB) transcription, resulting in the induction of tumor cell apoptosis.

  2. Drug

    Flurbiprofen axetil

    go.drugbank.com/drugs/DB14938
    Investigational

    Flurbiprofen axetil is under investigation in clinical trial NCT02043366 (Effect of Butorphanol Combined With Flurbiprofen Axetil on Preventing Hyperalgesia Induced by Remifentanil in Patients).

  3. Drug

    Dihydromyricetin

    go.drugbank.com/drugs/DB15645
    Investigational

    Dihydromyricetin is under investigation in clinical trial NCT03606694 (Effect of Dihydromirycetin on Glycemic Control, Insulin Sensitivity and Insulin Secretion in Type 2 Diabetes Mellitus).

  4. Drug

    Pirepemat

    go.drugbank.com/drugs/DB19165
    Investigational

    Pirepemat is under investigation in clinical trial NCT05258071 (A Clinical Study Evaluating Efficacy of Pirepemat on Falls Frequency in Patients With Parkinson's Disease (PD)).

  5. Drug

    RAPA-501-Allo

    go.drugbank.com/drugs/DB15890
    Investigational

    RAPA-501-ALLO is composed of T-cells extracted from healthy volunteers; these cells are then reprogrammed _ex vivo_ in a process that involves de-differentiation and re-differentiation.[L16483]

  6. Drug

    JNJ-54175446

    go.drugbank.com/drugs/DB15358
    Investigational

    JNJ-54175446 is under investigation in clinical trial NCT02933762 (A Study in Healthy Participants to Evaluate the Effect of JNJ-54175446 on Amyloid Biomarkers and Cytokine Profiles in Cerebrospinal Fluid

  7. Drug

    E5531

    go.drugbank.com/drugs/DB06447
    Experimental

    E5531 is an endotoxin antagonist.

  8. Drug

    Trenbolone

    go.drugbank.com/drugs/DB11551
    ExperimentalVet approved

    Plasma lipases then cleave the ester group in the bloodstream leaving free trenbolone. … Trenbolone, also known as trienolone or trienbolone, is a steroid used on livestock to increase muscle growth and appetite.

  9. Drug

    Epitizide

    go.drugbank.com/drugs/DB13989
    Experimental

    Epitizide is an agent, commonly found in combination [triamterene], used to produce diuresis.

  10. Drug

    P-nitrobiphenyl

    go.drugbank.com/drugs/DB12300
    ApprovedWithdrawn

    Pnb has been used in trials studying the treatment of Pelvic Organ Prolapse.