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Displaying results 5121 - 5130 of 6949 in total
  1. Drug

    PPL-100

    go.drugbank.com/drugs/DB05961
    Investigational

  2. Drug

    Pegdinetanib

    go.drugbank.com/drugs/DB05931
    Investigational

    As a result, CT-322 blocks all known ligands for VEGFR-2. … CT-322 is a proprietary Adnectin(TM) protein therapeutic that, in preclinical studies, specifically binds to vascular endothelial growth factor receptor 2 (VEGFR-2), which regulates the primary tumor angiogenesis

    Categories: Vascular Endothelial Growth Factor Receptor-2, antagonists & inhibitors
  3. Drug

    Hexobarbital

    go.drugbank.com/drugs/DB01355
    Experimental

    A barbiturate that is effective as a hypnotic and sedative.

  4. Target

    Tumor necrosis factor ligand superfamily member 11

    go.drugbank.com/bio_entities/BE0003517
    TargetHumans

    Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions ...

    Synonyms: Receptor activator of nuclear factor kappa-B ligand
  5. Target

    Hepatocyte nuclear factor 4-alpha

    go.drugbank.com/bio_entities/BE0004019
    TargetHumans

    Transcriptional regulator which controls the expression of hepatic genes during the transition of endodermal cells to hepatic progenitor cells, facilitating the recruitment of RNA pol II to the promoters of target genes (PubMed:30597922)...

    Synonyms: Nuclear receptor subfamily 2 group A member 1
  6. Drug

    HTPEP-001

    go.drugbank.com/drugs/DB18730
    Experimental

    It is being investigated for the treatment of fibrosis.[A263527]

  7. Drug

    Mesenchymal stem cell-derived exosomes

    go.drugbank.com/drugs/DB24445
    Investigational

    Mesenchymal Stem Cell-Derived Exosomes is under investigation in clinical trial NCT07183384 (MSC Exosome Therapy for Post-Preeclampsia Endothelial Dysfunction).

  8. Drug

    Hydroxyethylpromethazine

    go.drugbank.com/drugs/DB13840
    Experimental

    Categories: Antihistamines for Systemic Use
  9. Drug

    CPZEN-45

    go.drugbank.com/drugs/DB18077
    Experimental

    Categories: Drugs for Treatment of Tuberculosis
  10. Drug

    Dipyrithione

    go.drugbank.com/drugs/DB11327
    Approved

    [A32829] Interestingly, dipyrithione has been studied and shown to have cytotoxic and potent broad-spectrum antitumor activity, which suggests a potential basis for an anticancer drug development.