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Displaying results 5131 - 5140 of 10000 in total
  1. Drug

    Carboxin

    go.drugbank.com/drugs/DB04657
    ApprovedWithdrawn

    A systemic agricultural fungicide and seed treatment agent.

    Categories: Compounds used in a research, industrial, or household setting
  2. Drug

    UB-612

    go.drugbank.com/drugs/DB16444
    Investigational

    The UB-612 COVID-19 vaccine was developed by United Biomedical Inc Asia in Taipei as the first COVID-19 “multi-tope” protein-peptide vaccine made up of eight rationally designed components[L30653]. … It was able to reduce viral load and prevent COVID-19 infection in a mouse challenge model and in rhesus macaques[L30653, L30658].

  3. Drug

    AT-301

    go.drugbank.com/drugs/DB16507
    Investigational

    AT-301 was under investigation in clinical trial NCT01675284 to evaluate the safety, reactogenicity, and humoral immune responses to an inactivated H5N1 influenza vaccine

  4. Drug

    Proguanil

    go.drugbank.com/drugs/DB01131
    Approved

    It does this by inhibiting the enzyme, dihydrofolate reductase, which is involved in the reproduction of the parasite. … Proguanil is a prophylactic antimalarial drug, which works by stopping the malaria parasite, _Plasmodium falciparum_ and _Plasmodium vivax_, from reproducing once it is in the red blood cells.

  5. Target

    Neutral amino acid transporter B(0)

    go.drugbank.com/bio_entities/BE0000236
    TargetTransporterHumans

    Mediates D-serine release from the retinal glia potentially affecting NMDA receptor function in retinal neurons.

    Synonyms: Baboon M7 virus receptor, RD114/simian type D retrovirus receptor
  6. Drug

    Dalfopristin

    go.drugbank.com/drugs/DB01764
    Approved

    It is not effective against Enterococcus faecalis infections. … Dalfopristin inhibits the early phase of protein synthesis in the bacterial ribosome and quinupristin inhibits the late phase of protein synthesis.

  7. Target

    Deoxyhypusine hydroxylase

    go.drugbank.com/bio_entities/BE0018877
    TargetHumans

    Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate produced by deoxyhypusine synthase/DHPS on a critical lysine of the eukaryotic translation initiation factor 5A/eIF-5A. This is the second step of the post-tran...

    Synonyms: HEAT-like repeat-containing protein 1
  8. Target

    CD320 antigen

    go.drugbank.com/bio_entities/BE0019797
    TransporterHumans

    Receptor for transcobalamin saturated with cobalamin (TCbl) (PubMed:18779389). Plays an important role in cobalamin uptake (PubMed:18779389, PubMed:20524213).

    Synonyms: Transcobalamin receptor
  9. Drug

    Rebastinib

    go.drugbank.com/drugs/DB13005
    Investigational

    Rebastinib has been used in trials studying the treatment of Chronic Myeloid Leukemia. It is an inhibitor of Tie2 tyrosine kinase receptor and an antineoplastic agent.

  10. Drug

    Captodiame

    go.drugbank.com/drugs/DB09014
    Experimental

    Captodiame, also known as captodiamine, is an antihistamine which is used as a sedative and anxiolytic. It is a derivative of diphenhydramine. … Captodiame has been suggested for use in preventing benzodiazepine withdrawal syndrome.

    Categories: Serotonin Receptor Antagonists, Serotonin 5-HT2 Receptor Antagonists