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Dimethyl fumarate
go.drugbank.com/drugs/DB08908ApprovedInvestigationalIt is thought to involve dimethyl fumarate degradation to its active metabolite monomethyl fumarate (MMF) then MMF up-regulates the Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) pathway that is activated … [L43752] Dimethyl fumarate is marketed under the brand name Tecfidera, and it was the third oral disease-modifying agent for multiple sclerosis approved by the FDA, following [fingolimod] and [teriflunomide
Synonyms: (E)-But-2-enedioic acid dimethyl ester, 1,2-bis(methoxycarbonyl)-trans-ethyleneProducts: TECFIDERA 120 MG, YARDIX® 120 MGRocuronium
go.drugbank.com/drugs/DB00728ApprovedInvestigational[Sugammadex] is a γ-cyclodextrin derivative that has been introduced as a novel agent to reverse the action of rocuronium. … The drug is associated with the risk of developing allergic reactions in some high-risk patients, such as those with asthma.
Products: ANTARİN 100 MG/10 ML IV ENJEKSİYONLUK ÇÖZELTİ, 10 ADET, MUSCOBLOC 100 MG/10 ML İ.V. ENJEKSİYONLUK ÇÖZELTİ, 10 ADETAmphotericin B
go.drugbank.com/drugs/DB00681ApprovedInvestigationalmcg/mL in vitro. … Blastomyces dermatitidis, Rhodotorula, Cryptococcus neoformans, Sporothrix schenckii, Mucor mucedo, and Aspergillus fumigatus are all inhibited by concentrations of amphotericin B ranging from 0.03 to 1.0
Products: AMPHOLIP ®50 MG/10 ML, ABELCET 100 MG/20 ML IV INF. ICIN. SUS. ICEREN FLAKON, 1 ADETBeta carotene
go.drugbank.com/drugs/DB06755ApprovedNutraceutical[T158] Under the FDA, beta-carotene is considered as a generally recognized as safe substance (GRAS).[L2191]
Mixtures: ACECAP 20/200/200 MG YUMUŞAK KAPSÜL, 30 ADET, Folika-MGProducts: CAROVIT 20 MG YUMUSAK KAPSUL, 100 ADET, CAROVIT 20 MG YUMUSAK KAPSUL, 30 ADETAzelastine
go.drugbank.com/drugs/DB00972ApprovedInvestigationalAzelastine, a phthalazine derivative, is an antihistamine available as an intranasal spray for the treatment of allergic and vasomotor rhinitis and as an ophthalmic solution for the treatment of allergic … [L8240,L8270] It is a racemic mixture, though there is no noted difference in pharmacologic activity between enantiomers, and was first granted FDA approval in 1996.
Mixtures: DYMİSTA 137 MCG + 50 MCG BURUN SPREYİ, SÜSPANSİYON, 23 G, DYMİSTA 137 MCG + 50 MCG BURUN SPREYİ, SÜSPANSİYON, 6,4 GCategories: Heterocyclic Compounds, 1-RingRoxadustat
go.drugbank.com/drugs/DB04847ApprovedInvestigational[A245393] Roxadustat was first approved by the European Commission in August 2021.[L40323]
Categories: Heterocyclic Compounds, 2-RingProducts: Ernevod 20 mg Film Kaplı Tablet (12 adet), EVRENZO 20 MG FİLM KAPLI TABLET, 12 ADETAzithromycin
go.drugbank.com/drugs/DB00207ApprovedInvestigationalIn March 2020, a small study was funded by the French government to investigate the treatment of COVID-19 with a combination of azithromycin and the anti-malaria drug [hydroxychloroquine]. … It was initially approved by the FDA in 1991 [A174175].
Categories: Experimental Unapproved Treatments for COVID-19Products: AZITHROMYCIN FOR INJECTION 500 MG/VIAL , 10 ML LYO VIAL, ZITROMAX 200 MG/5ML ORAL SUSPANSIYON, 15 MLCefadroxil
go.drugbank.com/drugs/DB01140ApprovedInvestigationalVet approvedWithdrawnLong-acting, broad-spectrum, water-soluble, cephalexin derivative.
Categories: Heterocyclic Compounds, 2-RingProducts: CEFRADUR 1 G TABLET, 20 ADET, CEFRADUR 250 MG/5 ML ORAL SÜSPANSİYON HAZIRLAMAK İÇİN KURU TOZ, 60 MLCodeine
go.drugbank.com/drugs/DB00318ApprovedIllicitInvestigationalOpiates such as codeine are derived from the poppy plant, _Papaver somniferum_ (Papaveraceae). … [A175096] Codeine is utilized as a central analgesic, sedative, hypnotic, antinociceptive, and antiperistaltic agent, and is also recommended in certain diseases with incessant coughing.
Synonyms: 7,8-didehydro-4,5α-epoxy-3-methoxy-17-methylmorphinan-6α-ol, (5alpha,6alpha)-7,8-Didehydro-4,5-epoxy-3-methoxy-17-methylmorphinan-6-olMixtures: FENOKODIN 20 MG / 10 MG TABLET, 20 ADET, A-FERİN 300 MG/2 MG/10 MG KAPSÜL, 20 ADETDiazepam
go.drugbank.com/drugs/DB00829ApprovedIllicitInvestigationalVet approvedIt is used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal … (From Martindale, The Extra Pharmacopoeia, 30th ed, p589) Given diazepam's storied history as a commonly used and effective medication for a variety of indications, contemporary advancements in the
Synonyms: 7-chloro-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one, NRL-1Categories: Heterocyclic Compounds, 2-Ring