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Triazavirin
go.drugbank.com/drugs/DB15622InvestigationalTriazavirin is a guanine nucleotide analog antiviral originally developed in Russia that has shown efficacy against influenza A and B, including the H5N1 strain. … [A191709,A191625,A191916] It appears that Triazavirin has shown promise in reducing influenza disease severity and associated complications.
Categories: Heterocyclic Compounds, 1-RingRoxithromycin
go.drugbank.com/drugs/DB00778ApprovedInvestigationalWithdrawnIt is marketed in Australia as a treatment for respiratory tract, urinary and soft tissue infections. … Roxithromycin is a semi-synthethic macrolide antibiotic that is structurally and pharmacologically similar to [erythromycin], [azithromycin], or [clarithromycin].
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InhibitorsSynonyms: (9E)-erythromycin 9-(O-((2-methoxyethoxy)methyl)oxime)Omarigliptin
go.drugbank.com/drugs/DB11992InvestigationalOmarigliptin has been used in trials studying the treatment of Type 2 Diabetes Mellitus and Chronic Renal Insufficiency.
Categories: DPP-IV Inhibitors, Heterocyclic Compounds, 1-RingThiethylperazine
go.drugbank.com/drugs/DB00372ApprovedInvestigationalWithdrawnA dopamine antagonist that is particularly useful in treating the nausea and vomiting associated with anesthesia, mildly emetic cancer chemotherapy agents, radiation therapy, and toxins.
Synonyms: 2-(ethylthio)-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazineCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 3-RingAluminium monostearate
go.drugbank.com/drugs/DB01375ExperimentalAluminium monostearate is a salt of stearic acid and aluminium with the molecular formula Al(OH)2C18H35O2. … Also known as dihydroxyaluminium or dihydroxy(stearato)aluminium, it is used to form gels in the packaging of pharmaceuticals and in the preparation of colors for cosmetics.
Anpocogin
go.drugbank.com/drugs/DB06552InvestigationalRecombinant nematode anticoagulant protein c2 (rNAPc2) is a specific inhibitor of tissue factor (TF)/factor VIIa complex with novel antithrombotic activity. [A175642]
Synonyms: Recombinant nematode anticoagulant protein-2Citatuzumab Bogatox
go.drugbank.com/drugs/DB06072InvestigationalVB6-845 is a humanized antibody fragment targeting EpCAM fused with the deimmunized form of the cytotoxin Bouganin and is designed for systemic use against metastatic cancer. … VB6-845 has demonstrated effective cancer cell killing properties in pre-clinical tests.
Cephalexin
go.drugbank.com/drugs/DB00567ApprovedInvestigationalVet approved[A179071] Cephalexin is used to treat a number of susceptible bacterial infections through inhibition of cell wall synthesis.[A179083,L6547] Cephalexin was approved by the FDA on 4 January 1971. … Cephalexin is the first of the first generation cephalosporins.[A179071,A179074] This antibiotic contains a beta lactam and a dihydrothiazide.
Synonyms: (6R,7R)-7-{[(2R)-2-amino-2-phenylacetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-beta-(D-alpha-Amino-alpha-phenylacetylamino)-3-methyl-3-cephem-4-carboxylic acidInternational brands: L-KeflexXL019
go.drugbank.com/drugs/DB05243InvestigationalXL019 is a selective inhibitor of the cytoplasmic tyrosine kinase JAK2. An IND for XL019 was filed by Exelixis in May 2007.
Azosemide
go.drugbank.com/drugs/DB08961InvestigationalAzosemide is a loop diuretic used to treat hypertension, edema, and ascites.
Synonyms: 2-chloro-5-(1H-tetrazol-5-yl)-N4-2-thenylsulfanilamide, 5-(4'-chloro-5'-sulfamoyl-2'-thenylaminophenyl)tetrazoleCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-Ring