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Cabozantinib
go.drugbank.com/drugs/DB08875ApprovedInvestigationalCabozantinib was first approved in 2012 and is a non-specific tyrosine kinase inhibitor. … [L15123] In 2016, a capsule formulation (Cabometyx) was approved for the treatment of advanced renal cell carcinoma, and this same formulation gained additional approval in both the US and Canada in 2019
Categories: Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexProducts: CABOMETYX 40 MG FİLM KAPLI TABLET, 30 ADET, CABOMETYX 20 MG FİLM KAPLI TABLET, 30 ADETPolyvinyl alcohol
go.drugbank.com/drugs/DB11060ApprovedPolyvinyl alcohol is found in ophthalmic solutions as a lubricant to prevent irritation or to relieve dryness of the eyes [L2826]. … Polyvinyl alcohol is a water-soluble synthetic polymer obtained by polymerization of vinyl alcohol.
Mixtures: SUPRENIL STERIL OFTALMIK SUSPANSIYON 5 ML, FULLFRESH 5,60 MG/2,40 MG TEK DOZLUK GÖZ DAMLASI, ÇÖZELTİCategories: Compounds used in a research, industrial, or household settingLisdexamfetamine
go.drugbank.com/drugs/DB01255ApprovedInvestigationalLisdexamfetamine is a prodrug of [dextroamphetamine], a central nervous system stimulant known as d-amphetamine,[A40246] covalently attached to the naturally occurring amino acid L-lysine. … [A2230] Lisdexamfetamine is the first chemically formulated prodrug stimulant [A40246] and was first approved by the FDA in April 2008.[A2230] It was also approved by Health Canada in February 2009.
Products: VYVANSE® 40 MG CAPSULAS, SAMEXID® 30 MGTyphoid Vi polysaccharide vaccine
go.drugbank.com/drugs/DB10803ApprovedInvestigationalTyphoid Vi polysaccharide vaccine is a vaccine that is administered intramuscularly. … It is an active immunization for the prevention of typhoid fever caused by S typhi and is approved for use in persons two years of age or older.
Synonyms: Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strainProducts: TYPHIM VI 0,5 ML IM/SC ENJEKSİYON İÇİN ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET, TYPHIM VI INJECTION 0.025 mg/0.5 mlEconazole
go.drugbank.com/drugs/DB01127ApprovedA broad spectrum antimycotic with some action against Gram positive bacteria. It is used topically in dermatomycoses also orally and parenterally.
Mixtures: TRILON-E CREAM, Econazole Nitrate 1% / Niacinamide 4%Categories: P-glycoprotein inhibitors, Heterocyclic Compounds, 1-RingRoxadustat
go.drugbank.com/drugs/DB04847ApprovedInvestigationalRoxadustat is a first-in-class hypoxia-inducible factor prolyl hydroxylase inhibitor used to treat anemia associated with chronic kidney disease. … It works by reducing the breakdown of the hypoxia-inducible factor (HIF), which is a transcription factor that stimulates red blood cell production in response to low oxygen levels.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingProducts: Ernevod 20 mg Film Kaplı Tablet (12 adet), Ernevod 50 mg Film Kaplı Tablet (12 adet)Propiverine
go.drugbank.com/drugs/DB12278ApprovedPropiverine is a widely used antimuscarinic drug with a mixed mode of action in the treatment of symptoms associated with overactive bladder (OAB) [A32576]. … OAB has a negative impact on quality of life and may lead to leakage and inconvenient urinary accidents [L2327], [L2328].
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: MİCTONORM 5 MG KAPLI TABLET, 98 ADET, Mictonorm 45 mg Hartkapseln mit veränderter WirkstofffreisetzungZinc citrate
go.drugbank.com/drugs/DB11154ApprovedInvestigationalZinc citrate is a zinc salt of citric acid. It is available as dietary supplements as a treatment of zinc deficiency and source of zinc, which is an essential trace element.
Mixtures: Vitamin A C E W.niacinam.beta Car.and Min., Collag-ENProducts: Zinc 50 mgMaribavir
go.drugbank.com/drugs/DB06234ApprovedInvestigationalMaribavir is an inhibitor of the cytomegalovirus (CMV; HHV5) pUL97 kinase which is used to treat CMV infections in patients post-transplantation. … [A242557] Maribavir is novel in that it instead targets the CMV pUL97 kinase, thereby providing an effective alternative treatment option in cases of resistant infections.
Categories: Cytochrome P-450 Substrates, P-glycoprotein inhibitorsProducts: Livtencity 200 mg Film Kaplı Tablet (112 (56'lık 2 şişe) Adet), Livtencity 200 mg Film Kaplı Tablet (28 Adet)Armodafinil
go.drugbank.com/drugs/DB06413ApprovedInvestigational(a wholly owned subsidiary of Teva Pharmaceutical Industries Ltd.) and was approved by the U.S. Food and Drug Administration (FDA) in June 2007. … Research has shown that armodafinil significantly improves driving simulator performance in patients with SWD. Armodafinil consists of the (−)-R-enantiomer of the racemic modafinil.
Synonyms: (–)-2-[(R)-(diphenylmethyl)sulfinyl]acetamide, R-modafinilCategories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 CYP2B6 Inducers