Search
Sugemalimab
go.drugbank.com/drugs/DB16641ApprovedInvestigationalSugemalimab is a fully human, full-length anti-programmed death-ligand 1 (PD-L1) monoclonal antibody (of the IgG4 isotype) discovered by CStone Pharmaceuticals. … The antibody has also been granted the Breakthrough Therapy Designation by the FDA to treat relapsed or refractory extranodal natural killer (NK)/T-cell lymphoma (R/R ENKTL) and an orphan drug designation
Categories: PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitorsPolyethylene glycol 400
go.drugbank.com/drugs/DB11077ApprovedInvestigationalPolyethylene glycols (PEGs) are products made of condensed ethylene oxide and water that can contain various derivatives and have various functions.
Mixtures: Hydration PF, Systane Hydration PF Preservative FreeCategories: P-glycoprotein inhibitorsTriflupromazine
go.drugbank.com/drugs/DB00508ApprovedVet approvedA phenothiazine used as an antipsychotic agent and as an antiemetic.
Categories: P-glycoprotein inhibitors, Dopamine D2 Receptor AntagonistsDasatinib
go.drugbank.com/drugs/DB01254ApprovedInvestigationalDasatinib is an orally available multikinase inhibitor indicated for the treatment of Philadelphia chromosome (Ph)-positive leukemias. … [A11377] Unlike [imatinib], another tyrosine kinase used for the treatment of CML and Ph-positive ALL, dasatinib inhibits the active and inactive conformations of the ABL kinase domain.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesPolysorbate 80
go.drugbank.com/drugs/DB11063ApprovedInvestigationalIn food or pharmaceutical products, it can act as an emulsifier. … Polysorbate, a substance formulated by the reaction of sorbitan fatty acid ester (a nonionic surfactant) with ethylene oxide, is used in many foreign countries, including the U.S. and the EU, where it
Mixtures: Refresh Digital PF, ENDURA® UDCategories: P-glycoprotein inhibitors, Cytochrome P-450 CYP3A InhibitorsMagnesium chloride
go.drugbank.com/drugs/DB09407ApprovedInvestigationalMagnesium chloride salts are highly soluble in water and the hydrated form of magnesium chloride can be extracted from brine or sea water.
Mixtures: ELETTROLITICA DI REINTEGRAZIONE PH 7,4 CON SODIO GLUCONATO FKI, ELETTROLITICA DI REINTEGRAZIONE PH 7,4 CON SODIO GLUCONATO FKILutetium Lu-177 vipivotide tetraxetan
go.drugbank.com/drugs/DB16778ApprovedInvestigationalLutetium Lu-177 vipivotide tetraxetan is a radioligand therapeutic agent. … [L43787] In December 2022, lutetium Lu-177 vipivotide tetraxetan was approved by the EMA.[L43787,L45533]
Synonyms: Lu-177-PSMA-617, lutetium Lu 177-PSMA-617Amisulpride
go.drugbank.com/drugs/DB06288ApprovedInvestigationalAmisulpride is a benzamide derivative and a dopamine receptor antagonist that selectively works on dopamine D2 and D3 receptors. … [L32764] Amisulpride is also used as an antiemetic agent.
Categories: P-glycoprotein substrates, Dopamine D2 Receptor AntagonistsMethylprednisolone hemisuccinate
go.drugbank.com/drugs/DB14644ApprovedInvestigationalA water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies.
Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 InducersProducts: SOLU-MEDROL DE 40 MG SOLUCIONAlprostadil
go.drugbank.com/drugs/DB00770ApprovedInvestigationalThis drug causes vasodilation by directly affecting vascular and ductus arteriosus (DA) smooth muscle, preventing or reversing the functional closure of the DA that occurs shortly after birth. … In 1996, the FDA approved the use of alprostadil, administered either with an intracavernosal injection or an intraurethral suppository, for the treatment of erectile dysfunction, and it is used in men
International brands: Kai Tong, Caverject DC