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Displaying results 521 - 530 of 10000 in total
  1. Drug

    TD-0903

    go.drugbank.com/drugs/DB16463
    Investigational

    TD-0903 was investigated in clinical trials for its potential to treat acute lung injury (ALI) associated with COVID-19, including NCT04350736, NCT05091723 (a pharmacokinetics study in healthy participants

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: (S)-(3-(DIMETHYLAMINO)AZETIDIN-1-YL)(2-(6-(2-ETHYL-4-HYDROXYPHENYL)-1H-INDAZOL-3-YL)-5-ISOPROPYL-4,5,6,7-TETRAHYDRO-3H-IMIDAZO(4,5-C)PYRIDIN-6-YL)METHANONE, (3-(DIMETHYLAMINO)AZETIDIN-1-YL)((6S)-2-(6-(2-ETHYL-4-HYDROXYPHENYL)-1H-INDAZOL-3-YL)-5-(PROPAN-2-YL)-4,5,6,7-TETRAHYDRO-1H-IMIDAZO(4,5-C)PYRIDIN-6-YL)METHANONE
  2. Target

    Cathepsin S

    go.drugbank.com/bio_entities/BE0001646
    TargetHumans

    Thiol protease (PubMed:30612035). Key protease responsible for the removal of the invariant chain from MHC class II molecules and MHC class II antigen presentation (PubMed:30612035). The bond-specificity of this proteinase is in part sim...

    Polypeptides: Cathepsin S
  3. Target

    Aminopeptidase S

    go.drugbank.com/bio_entities/BE0002747
    TargetStreptomyces griseus

    An exopeptidase specific for larger hydrophobic amino acids (especially leucine), no cleavage occurs if the next residue is proline (PubMed:8444149).

    Polypeptides: Aminopeptidase S
  4. Drug

    Dapiglutide

    go.drugbank.com/drugs/DB19182
    Investigational

    Dapiglutide is under investigation in clinical trial NCT05788601 (Dapiglutide for the Treatment of Obesity).

    Synonyms: -glutamyl)- (a2>aib (2-methylalanine), d3>e, s7>t, d8>s, m10>l, n11>a, n16>k, l17>q, n24>a, t29>h)human glucagonlike peptide 2 (glp-2), L-ASPARTIC ACID, L-HISTIDYL-2-METHYLALANYL-L-.ALPHA.-GLUTAMYLGLYCYL-L-SERYL-L-PHENYLALANYL-L-THREONYL-L-SERYL-L-.ALPHA.-GLUTAMYL-L-LEUCYL-L-ALANYL-L-THREONYL-L-ISOLEUCYL-L-LEUCYL-L-.ALPHA.
  5. Drug

    Magnesium

    go.drugbank.com/drugs/DB14513
    ApprovedInvestigational

    Magnesium is classified as an alkaline earth metal and has 2 hydration shells. … [A188120,L2601] Magnesium is an important enzyme cofactor and is essential to several metabolic processes.

    Mixtures: Kordel"s Bio-Liquid Women"s Multi With Fish Oil Vegicap, KORDEL`S EXECUTIVE B TABLETProducts: MAGNEROT A 500 BEUTEL, MG 5 LONGORAL
  6. Target

    S-methylmethionine--homocysteine S-methyltransferase BHMT2

    go.drugbank.com/bio_entities/BE0002249
    TargetEnzymeHumans

    Converts homocysteine to methionine using S-methylmethionine (SMM) as a methyl donor

    Polypeptides: S-methylmethionine--homocysteine S-methyltransferase BHMT2Synonyms: Betaine--homocysteine S-methyltransferase 2
  7. Drug

    CA-074 methyl ester

    go.drugbank.com/drugs/DB07223
    Experimental

    CA-074 methyl ester (CA-074Me) is a cell-permeable cathepsin B inhibitor. It is converted by cellular esterases to CA-074.[A258234,A258239]

    Categories: Cathepsin B, antagonists & inhibitorsSynonyms: (S)-methyl 1-((2S,3S)-3-methyl-2-((2S,3S)-3-(propylcarbamoyl)oxirane-2-carboxamido)pentanoyl)pyrrolidine-2-carboxylate, Methyl (2S)-1-[(2S,3S)-3-methyl-2-[[(2S,3S)-3-(propylcarbamoyl)oxirane-2-carbonyl]amino]pentanoyl]pyrrolidine-2-carboxylate
  8. Drug

    A-16L

    go.drugbank.com/drugs/DB18270
    Experimental

    Synonyms: MAVEROPEPIMUT-S COMPONENT A16L, L-ALANYL-L-GLUTAMINYL-L-TYROSYL-L-ISOLEUCYL-L-LYSYL-L-ALANYL-L-ASPARAGINYL-L-SERYL-L-LYSYL-L-PHENYLALANYL-L-ISOLEUCYLGLYCYL-L-ISOLEUCYL-L-THREONYL-L-.ALPHA.-GLUTAMYL-L-LEUCINE
  9. Target

    Neuropeptide S receptor

    go.drugbank.com/bio_entities/BE0000948
    TargetHumans

    G protein-coupled receptor for neuropeptide S (NPS) (PubMed:15947423, PubMed:16720571, PubMed:16790440).

    Polypeptides: Neuropeptide S receptor
  10. Target

    S-ribosylhomocysteine lyase

    go.drugbank.com/bio_entities/BE0001462
    TargetDeinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)

    Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

    Polypeptides: S-ribosylhomocysteine lyase