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Lanthanum carbonate
go.drugbank.com/drugs/DB06792ApprovedIt is a large pill that requires thorough chewing to avoid choking and other gastrointestinal adverse effects. … Lanthanum carbonate is a phosphate binder marketed under the trade name _Fosrenol_ by Shire Pharmaceuticals.
Synonyms: Lanthanum(3+) carbonateProducts: FOSRENOL 500 MG, FOSRENOL 750 MG.Pramocaine
go.drugbank.com/drugs/DB09345ApprovedPramocaine (also known as pramoxine or pramoxine HCI) is a topical anesthetic and antipruritic. … It is used for many dermatological and anorectal/anogenital conditions including minor cuts/burns, insect bites, hives/rashes due to poison ivy exposure, hemorrhoids and other anorectal/anogenital disorders
Mixtures: L-Topical CALAMINE 8% PRAMOXINE HCL 1%, Pomada De La Campana Triple Antibiotic Pain ReliefCategories: Heterocyclic Compounds, 1-Ring, Antihistamines, Anesthetics, Etc.Josamycin
go.drugbank.com/drugs/DB01321InvestigationalA macrolide antibiotic from Streptomyces narbonensis. The drug has antimicrobial activity against a wide spectrum of pathogens.
Synonyms: leucomycin V 3-acetate 4B-(3-methylbutanoate), leucomycin V 3-acetate 4β-(3-methylbutanoate)Products: Josalid 250 mg/5 ml - Saft für Kinder, Josalid 375 mg/5 ml - Saft für KinderAsciminib
go.drugbank.com/drugs/DB12597ApprovedInvestigationalMore specifically, it is an inhibitor of the ABL1 kinase activity of the BCR-ABL1 fusion protein[L38995] which serves as a driver of CML proliferation in most patients with the disease. … [L39005] It has also shown benefit in Ph+ CML with the T315I mutation, which produces a mutant BCR-ABL1 which is typically treatment-resistant as compared to wild-type BCR-ABL1.
Categories: Heterocyclic Compounds, 1-Ring, P-glycoprotein inhibitorsProducts: AZEVAY 20 MG FİLM KAPLI TABLET , 60 ADET, AZEVAY 40 MG FİLM KAPLI TABLET , 60 ADETRadium Ra 223 dichloride
go.drugbank.com/drugs/DB08913ApprovedInvestigationalThe FDA label includes a warning that Radium Ra 223 Dichloride should not be used in women who are pregnant or may become pregnant due to the high risk of fetal harm. … As a cation, radium mimics calicum and binds to hydroxyapatite, which is a bone mineral found in areas of high bone turnover as seen in bone metastases.
Synonyms: Radium chloride Ra-223, Radium (Ra-223) dichlorideProducts: XOFIGO 1100 KBQ/ML IV ENJEKSIYON IÇIN ÇÖZELTI IÇEREN FLAKON,1 ADET, XOFIGO®Propylthiouracil
go.drugbank.com/drugs/DB00550ApprovedA thiourea antithyroid agent. Propythiouracil inhibits the synthesis of thyroxine and inhibits the peripheral conversion of throxine to tri-iodothyronine. … It is used in the treatment of hyperthyroidism. (From Martindale, The Extra Pharmacopeoia, 30th ed, p534)
Categories: Heterocyclic Compounds, 1-RingSynonyms: 6-propyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one, 6-Propyl-2-thio-2,4(1H,3H)pyrimidinedioneMeasles virus vaccine live attenuated
go.drugbank.com/drugs/DB10315ApprovedInvestigationalMeasles virus vaccine live attenuated is a live virus vaccine for simultaneous vaccination against measles, which is a common childhood disease. … The vaccine is prepared from the attenuated line of measles virus, derived from Enders' attenuated Edmonston strain and propagated in chick embryo cell culture.
Mixtures: TRESIVAC 0,5 ML SC ENJEKSIYONLUK ÇÖZELTI IÇIN LIYOFILIZE TOZ IÇEREN FLAKON, 1 ADET, M-M-R IISynonyms: Measles virus live antigen, ATinzaparin
go.drugbank.com/drugs/DB06822ApprovedInvestigationalIt is a heterogeneous mixture of with an average molecular weight between 5500 and 7500 daltons. … LMWHs are less effective at inactivating factor IIa due to their shorter length compared to unfractionated heparin.
Products: INNOHEP INYECTABLE VIAL 2 MG 10.000 UI/ML., INNOHEP INJECTION 14, 000 Anti-Xa IU/0.7mlAbemaciclib
go.drugbank.com/drugs/DB12001ApprovedInvestigationalAbemaciclib is an antitumor agent and dual inhibitor of cyclin-dependent kinases 4 (CDK4) and 6 (CDK6) that are involved in the cell cycle and promotion of cancer cell growth in case of unregulated activity … It is either given alone in patients who has undergone endocrine therapy and chemotherapy after the metastasis of cancer, or in combination with [DB00947].
Categories: MATE 1 Substrates with a Narrow Therapeutic Index, MATE 1 InhibitorsProducts: VERZENIO® 100 MG, VERZENIO® 150 MGErlotinib
go.drugbank.com/drugs/DB00530ApprovedInvestigationalRecent studies demonstrate that erlotinib is also a potent inhibitor of JAK2V617F, which is a mutant form of tyrosine kinase JAK2 found in most patients with polycythemia vera (PV) and a substantial proportion … Erlotinib binds to the epidermal growth factor receptor (EGFR) tyrosine kinase in a reversible fashion at the adenosine triphosphate (ATP) binding site of the receptor.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexSynonyms: [6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4-yl]-(3-ethynyl-phenyl)-amine