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Displaying results 5321 - 5330 of 10000 in total
  1. Target

    Transcriptional enhancer factor TEF-5

    go.drugbank.com/bio_entities/BE0018748
    TargetHumans

    Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a ki...

    Polypeptides: Transcriptional enhancer factor TEF-5Synonyms: DTEF-1
  2. Target

    Ribitol 5-phosphate transferase FKRP

    go.drugbank.com/bio_entities/BE0019722
    TargetHumans

    -1,3-glucuronic acid-beta-1 (PubMed:25279699, PubMed:26923585, PubMed:27194101, PubMed:29477842, PubMed:31949166) … Catalyzes the transfer of a ribitol 5-phosphate from CDP-L-ribitol to the ribitol 5-phosphate previously attached by FKTN/fukutin to the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta

    Polypeptides: Ribitol 5-phosphate transferase FKRPSynonyms: Ribitol-5-phosphate transferase
  3. Drug

    Ponatinib

    go.drugbank.com/drugs/DB08901
    ApprovedInvestigational

    Ponatinib is a novel Bcr-Abl tyrosine kinase inhibitor that is especially effective against the T315I mutation for the treatment of chronic myeloid leukemia. FDA approved on December 14, 2012.

    Categories: Heterocyclic Compounds, 1-Ring, P-glycoprotein substrates with a Narrow Therapeutic IndexProducts: ICLUSIG® 15 MG TABLETAS RECUBIERTAS, ICLUSIG TABLET 15 MG
  4. Drug

    Fosinopril

    go.drugbank.com/drugs/DB00492
    ApprovedInvestigational

    ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). … Fosinopril is a phosphinic acid-containing ester prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications.

    Mixtures: MONOPRIL PLUS 10 MG/12.5 MG TABLET, 28 ADET, MONOPRIL PLUS 20 MG/12.5 MG TABLET, 28 ADETCategories: Agents Acting on the Renin-Angiotensin System
  5. Indication

    Kraurosis Vulvae

    go.drugbank.com/conditions/DBCOND0114418
    Drugs: Conjugated estrogens · Estradiol
    Synonyms: Lichen sclerosus et atrophicus, Lichen sclerosus et atropicus
  6. Drug

    Intermedine

    go.drugbank.com/drugs/DB17612
    Investigational

    Synonyms: N-acetyl-acth(1-13)-amide, Valinamide, acetyl-l-seryl-l-tyrosyl-l-seryl-l-methionyl-l-glutamyl-l-histidyl-l-phenylalanyl-l-arginyl-l-tryptophyl-glycyl-l-lysyl-l-prolyl-, l-Categories: Heterocyclic Compounds, 2-Ring
  7. Drug

    Eltrombopag

    go.drugbank.com/drugs/DB06210
    ApprovedInvestigational

    ITP is a condition that may cause unusual bruising or bleeding due to an abnormally low number of platelets in the blood. … Eltrombopag has also been recently approved (late 2012) for the treatment of thrombocytopenia (low blood platelet counts) in patients with chronic hepatitis C to allow them to initiate and maintain interferon-based

    Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 SubstratesProducts: REVOLADE ® TABLETAS 50 MG, REVOLADE® TABLETAS 25 MG
  8. Drug

    Chlorprothixene

    go.drugbank.com/drugs/DB01239
    ApprovedInvestigationalWithdrawn

    Chlorprothixene exerts strong blocking effects by blocking the 5-HT2 D1, D2, D3, histamine H1, muscarinic and alpha1 adrenergic receptors. … Chlorprothixene is a typical antipsychotic drug of the thioxanthene (tricyclic) class.

    Categories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2A Receptor AntagonistsProducts: Truxal 15 mg - Filmtabletten, Truxal 50 mg - Filmtabletten
  9. Drug

    Yellow fever vaccine

    go.drugbank.com/drugs/DB10805
    ApprovedInvestigational

    Yellow fever vaccine prevents against Yellow Fever, a viral hemorrhagic disease caused by the transmission of a _flavivirus_ through the bite of an infected mosquito. … The World Health Organization recommends routine vaccination in countries where Yellow Fever is endemic, and for travellers going to endemic areas as proof of vaccination is often a requirement at border

    Synonyms: Yellow fever virus live antigen, AProducts: STAMARIL 0,5 ML IM/SC ENJEKSİYON İÇİN LİYOFİLİZE TOZ İÇEREN FLAKON VE ÇÖZÜCÜ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET, STAMARIL ®
  10. Drug

    Coagulation Factor IX (Recombinant)

    go.drugbank.com/drugs/DB00100
    Approved

    It has a primary amino acid sequence that is identical to the Ala148 allelic form of human factor IX, and has structural and functional characteristics similar to those of endogenous factor IX. … medium that is then processed and purified for use as a pharmaceutical agent.

    Products: BENEFIX 250 IU IV ENJEKSIYONLUK COZELTI ICIN TOZ VE COZUCU, 1 ADET, BENEFIX 500 IU IV ENJEKSIYONLUK COZELTI ICIN TOZ VE COZUCU, 1 ADET