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Larotrectinib
go.drugbank.com/drugs/DB14723ApprovedInvestigationalIt was notable for being the second tissue-agnostic chemotherapy ever approved by the FDA.[L4847]. On April 10, 2025, the FDA granted full drug approval.[L52805] … [L49821] Upon administration, larotrectinib binds to Trk, thereby preventing neurotrophin-Trk interaction and Trk activation, which results in both the induction of cellular apoptosis and the inhibition
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: VITRAKVI 100 MG SERT KAPSÜL, 56 ADET, VITRAKVI 25 MG SERT KAPSÜL, 56 ADETTenoxicam
go.drugbank.com/drugs/DB00469ApprovedInvestigationalTenoxicam, an antiinflammatory agent with analgesic and antipyretic properties, is used to treat osteoarthritis and control acute pain.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesProducts: TENOKTIL 20 MG KAPSÜL, 10 ADET, TILCOTIL 20 MG 10 SUPPMagnesium hydroxide
go.drugbank.com/drugs/DB09104ApprovedInvestigationalMagnesium hydroxide is an inorganic compound. It is naturally found as the mineral brucite. Magnesium hydroxide can be used as an antacid or a laxative in either an oral liquid suspension or chewable tablet form. Additionally, magnesium ...
Mixtures: TRIGAST 10 MG/800 MG/165 MG ÇİĞNEME TABLETİ, 6 ADET, ACİDPASS 10 MG/800 MG/165 MG ÇİĞNEME TABLETİ, 2 ADETProducts: MAGNESIE CALCINEE SABA 400 MG SÜSPANSİYON HAZIRLAMAK İÇİN TOZ, 100 G, MAGNESIE CALCİNEE 400 MG SÜSPANSİYON HAZIRLAMAK İÇİN KURU TOZ, 100 GMidazolam
go.drugbank.com/drugs/DB00683ApprovedIllicitInvestigational[A173842] It belongs to a class of drugs called _benzodiazepines_. This drug is unique from others in this class due to its rapid onset of effects and short duration of action. … and endoscopic procedures as pre-anesthetic medication, and as an adjunct to local anesthesia.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsProducts: DORMICUM AMPOLLAS 50 MG / 10 ML, MIZOLAM® 50 MG/10 ML SOLUCIÓN INYECTABLEPamidronic acid
go.drugbank.com/drugs/DB00282ApprovedInvestigationalPamidronic acid is a second generation, nitrogen containing bisphosphonate similar to [neridronic acid] and [alendronic acid].[A203111] Pamidronic acid was first described in the literature in 1977.
Products: AREDIA 90 MG/10 ML FLAKON, 1 ADET, PAMISOL CONCENTRATED INJECTION 90 mg/10 mlAdenosine
go.drugbank.com/drugs/DB00640ApprovedInvestigational[A229828] Adenosine is indicated as an adjunct to thallium-201 in myocardial perfusion scintigraphy,[L31983] though it is rarely used in this indication, having largely been replaced by [dipyridamole] … [L31998] Adenosine was granted FDA approval on 30 October 1989.[L31978]
Synonyms: (2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diolMixtures: Return 10 Recovery Balm, Return 10 TIME LOCK PROGRAMEpinastine
go.drugbank.com/drugs/DB00751ApprovedIt has a multi-action effect that inhibits the allergic response in 3 ways: 1. stabilizes mast cells by preventing mast cell degranulation to control the allergic response, 2. prevents histamine binding … to both the H1- and H2-receptors to stop itching and provide lasting protection, and 3. prevents the release of proinflammatory chemical mediators from the blood vessel to halt progression of the allergic
Categories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2A Receptor AntagonistsProducts: FLURINOL COMPRIMIDOS RECUBIERTOS 10 MG., FLURINOL ® JARABE 0.2 G / 100 MLLorazepam
go.drugbank.com/drugs/DB00186ApprovedInvestigational[A957] It was developed by DJ Richards, presented and marketed initially by Wyeth Pharmaceuticals in the USA in 1977. … The first historic FDA label approval is reported in 1985 by the company Mutual Pharm.[L5095]
Synonyms: o-Chloroxazepam, o-ChlorooxazepamProducts: Temesta 1,0 mg - Tabletten, TAVOR 1.0Neostigmine
go.drugbank.com/drugs/DB01400ApprovedInvestigationalVet approvedA cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine.
Synonyms: (m-Hydroxyphenyl)trimethylammonium dimethylcarbamate, m-TrimethylammoniumphenyldimethylcarbamateProducts: PLANTIGMIN 0,5 MG/ML ENJEKSİYONLUK ÇÖZELTİ, 100 ADET, PLANTIGMIN 0,5 MG/ML ENJEKSİYONLUK ÇÖZELTİ, 50 ADETCalcium carbonate
go.drugbank.com/drugs/DB06724ApprovedInvestigationalCalcium carbonate may also be used as a nutritional supplement or to treat hypocalcemia. … It is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions. Subsequent increases in pH may inhibit the action of pepsin.
Mixtures: PRONAT 500 mg+267 mg+160 mg/10 ml ORAL SÜSPANSIYON, 200 ML, GASVİN 500 MG + 267 MG + 160 MG / 10 ML SÜSPANSİYON, 200 MLProducts: ANTI-FOSFAT CC 500 MG TABLET, 100 ADET, EFERCAL 500 MG EFERVESAN TABLET, 10 ADET