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Dopamine
go.drugbank.com/drugs/DB00988ApprovedInvestigationalDopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (receptors, dopamine) mediate its action. … One of the catecholamine neurotransmitters in the brain. It is derived from tyrosine and is the precursor to norepinephrine and epinephrine.
Mixtures: INYECCION DE CLORHIDRATO DE DOPAMINA EN DEXTROSA AL 5% USP (1600 MCG/ML), Myocard-DXCategories: Compounds used in a research, industrial, or household settingMoclobemide
go.drugbank.com/drugs/DB01171ApprovedInvestigationalDue to negligible anticholinergic and antihistaminic actions, moclobemide has been better tolerated than tri- or heterocyclic antidepressants [A31901]. … TCA) or selective serotonin reuptake inhibitors (SSRIs).
Synonyms: 4-Chlor-N-(2-morpholinoethyl)benzamid, p-Chloro-N-(2-morpholinoethyl)benzamideCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeMesalazine
go.drugbank.com/drugs/DB00244ApprovedInvestigationalof mesalazine within microgranules [A174019]. … the risk of colorectal cancer in conditions like ulcerative colitis is maintained.
Categories: Analgesics, Non-NarcoticProducts: SULIMAX® 500 MG TABLETAS CON CUBIERTA ENTERICA, SALOFALK 250 MG TABLETAS CON RECUBRIMIENTO ENTERICOFolic acid
go.drugbank.com/drugs/DB00158ApprovedInvestigationalNutraceuticalVet approvedThis important pathway, which is required for de novo synthesis of nucleic acids and amino acids, is disrupted by anti-metabolite therapies such as [DB00563] as they function as DHFR inhibitors to prevent … Folic acid, also known as folate or Vitamin B9, is a member of the B vitamin family and an essential cofactor for enzymes involved in DNA and RNA synthesis.
Synonyms: N-pteroyl-L-glutamic acid, N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acidMixtures: Pnv-VP-U, Edge OBPramipexole
go.drugbank.com/drugs/DB00413ApprovedInvestigationalliving due to symptoms that progress over time [A176858]. … Parkinson's Disease is one of the most common neurodegenerative disorders and causes a high level of disability in patients [A176855], leading to increased difficulty in performing activities of daily
Synonyms: (S)-N 6-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamineProducts: Nu-pramipexole, MIRAPEX ® ER 1.5 MG TABLETAS DE LIBERACIÓN PROLONGADAFlotufolastat F-18
go.drugbank.com/drugs/DB17851ApprovedInvestigational[A259846] In May 2023, the FDA approved the use of flotufolastat F-18 for PET of PSMA-positive lesions in men with prostate cancer with suspected metastasis who are candidates for initial definitive … therapy or suspected recurrence based on elevated serum prostate-specific antigen (PSA) level.
Doxorubicin
go.drugbank.com/drugs/DB00997ApprovedInvestigational[A1573,A257614,L45231] However, one of the major side effects of doxorubicin is cardiotoxicity, which excludes patients with poor heart function and requires treatment termination once the maximally tolerated … Doxorubicin is a cytotoxic anthracycline antibiotic isolated from cultures of Streptomyces peucetius var. caesius along side with daunorubicin, another cytotoxic agent, in 1970.
Products: DOXORUBICIN HCL OC 2MG/ML, DOXOLEM RUAtazanavir
go.drugbank.com/drugs/DB01072ApprovedInvestigationalAtazanavir is distinguished from other PIs in that it can be given once daily (rather than requiring multiple doses per day) and has lesser effects on the patient's lipid profile (the amounts of cholesterol … Like other protease inhibitors, it is used only in combination with other HIV medications. The U.S. Food and Drug Administration (FDA) approved atazanavir on June 20, 2003.
Categories: Antivirals used in combination for the treatment of HIV infectionsProducts: ATAZANAVIR DR. REDDY'STreprostinil
go.drugbank.com/drugs/DB00374ApprovedInvestigationalHowever, the use of epoprostenol is limited due to its short half-life (3-5 min) and instability at room temperature. … Treprostinil is a stable tricyclic analogue of prostacyclin[A248770] that promotes the vasodilation of pulmonary and systemic arterial vascular beds and the inhibition of platelet aggregation.
Products: TREPROSTINIL DR. REDDY'SMycophenolic acid
go.drugbank.com/drugs/DB01024ApprovedInvestigational[A249175] This regimen can be used in place of the older anti-proliferative [azathioprine] due to its stronger immunosuppressive potency. … Mycophenolic acid is used in immunosuppressive regimens as part of a triple therapy that includes a calcineurin inhibitor (ciclosporin or tacrolimus) and prednisolone.
Products: MICOFENOLATO DE MOFETILO, MICOFENOLATO DE MOFETILO CAPSULAS 250 MG