Search
Primaquine
go.drugbank.com/drugs/DB01087ApprovedInvestigationalAn aminoquinoline that is given by mouth to produce a radical cure and prevent relapse of vivax and ovale malarias following treatment with a blood schizontocide. … It has also been used to prevent transmission of falciparum malaria by those returning to areas where there is a potential for re-introduction of malaria.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesSynonyms: 6-Methoxy-8-(4-amino-1-methylbutylamino)quinoline, 8-((4-Amino-1-methylbutyl)amino)-6-methoxyquinolineMetformin
go.drugbank.com/drugs/DB00331ApprovedInvestigationalIt is commonly described as an "insulin sensitizer", leading to a decrease in insulin resistance and a clinically significant reduction of plasma fasting insulin levels. … [A36559] Metformin was first approved in Canada in 1972,[A36552] and received subsequent FDA approval in the US in 1995.[L12207]
Mixtures: Nb-sitagliptin-metformin, Nb-sitagliptin-metforminCategories: Drugs Used in Diabetes, MATE 1 SubstratesDolutegravir
go.drugbank.com/drugs/DB08930ApprovedInvestigational[A31342] Dolutegravir was developed by ViiV Healthcare and FDA-approved on August 12, 2013. … [A7514] The effect of this drug has no homology in human host cells, which gives it excellent tolerability and minimal toxicity.
Mixtures: TRIUMEQ® 50 MG / 600 MG / 300 MGCategories: Antivirals used in combination for the treatment of HIV infections, MATE 1 InhibitorsN-[[2-METHYL-4-HYDROXYCARBAMOYL]BUT-4-YL-N]-BENZYL-P-[PHENYL]-P-[METHYL]PHOSPHINAMID
go.drugbank.com/drugs/DB08507ExperimentalSynonyms: N-[[2-METHYL-4-HYDROXYCARBAMOYL]BUT-4-YL-N]-BENZYL-P-[PHENYL]-P-[METHYL]PHOSPHINAMIDTinzaparin
go.drugbank.com/drugs/DB06822ApprovedInvestigationalTinzaparin is a low molecular weight heparin (LMWH), produced by enzymatic depolymerization of unfractionated heparin from porcine intestinal mucosa. … It is an anticoagulant and considered an antithrombotic. Tinzaparin must be given either subcutaneously or parenterally.
Products: INNOHEP INYECTABLE VIAL 2 MG 10.000 UI/ML., INNOHEP INYECTABLE VIAL 2 ML. 20.000 UI/ML.Ambrosia artemisiifolia pollen
go.drugbank.com/drugs/DB10385ApprovedAmbrosia artemisiifolia pollen is the pollen of the Ambrosia artemisiifolia plant. Ambrosia artemisiifolia pollen is mainly used in allergenic testing.
Mixtures: 3-ragweed Mix, Giant/short/western PollenProducts: LAIS Ambrosia 1000 UA SublingualtablettenDiclofenac
go.drugbank.com/drugs/DB00586ApprovedInvestigationalVet approvedDiclofenac was first approved by the FDA in July 1988 under the trade name Voltaren, marketed by Novartis (previously Ciba-Geigy).[L7360] … Diclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID).
Synonyms: [2-(2,6-dichloroanilino)phenyl]acetic acid, 2-((2,6-dichlorophenyl)amino)benzeneacetic acidInternational brands: Nu-DicloPhenolphthalein
go.drugbank.com/drugs/DB04824ApprovedWithdrawnPhenolphthalein was withdrawn in Canada due to concerns with carcinogenicity in 1997.
Synonyms: 3,3-Bis(4-hydroxyphenyl)phthalideInternational brands: Feen-a-mint gum, Feen-a-mint laxative mintsSulfinpyrazone
go.drugbank.com/drugs/DB01138ApprovedA uricosuric drug that is used to reduce the serum urate levels in gout therapy. It lacks anti-inflammatory, analgesic, and diuretic properties.
Categories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 SubstratesSynonyms: 1,2-Diphenyl-3,5-dioxo-4-(2-phenylsulfinylethyl)pyrazolidine, 1,2-Diphenyl-4-(2'-phenylsulfinethyl)-3,5-pyrazolidinedioneNorethisterone
go.drugbank.com/drugs/DB00717ApprovedInvestigationalas an oral contraceptive until 1962. … [L9527,L10301,L10304,L10307] First derived in 1951 in Mexico City, norethisterone was originally intended for use as a remedy for irregular menstruation and endometriosis, and was not marketed for use
Synonyms: 17-hydroxy-19-nor-17-α-pregn-4-en-20-yn-3-one, 17-hydroxy-19-nor-17α-pregn-4-en-20-yn-3-oneInternational brands: Primolut-N