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Displaying results 531 - 540 of 8411 in total
  1. Target

    3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7

    go.drugbank.com/bio_entities/BE0000184
    TargetHumans

    Converts estrone (E1) to a more potent estrogen, 17beta-estradiol (E2) (PubMed:12574203, PubMed:12732193, PubMed:19772289).

    Synonyms: Estradiol 17-beta-dehydrogenase 7
  2. Drug

    Hydroxyprogesterone caproate

    go.drugbank.com/drugs/DB06789
    Approved

    It is an ester derivative of 17α-hydroxyprogesterone formed from caproic acid (hexanoic acid). … In April 2023, the FDA withdrew its approval of Makena and its generics given an unfavorable risk-to-benefit assessment.[L46113]

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 InducersSynonyms: Caproato de hidroxiprogesterona
  3. Drug

    Rilpivirine

    go.drugbank.com/drugs/DB08864
    ApprovedInvestigational

    [L31193] While previously administered once-monthly only, this combination product was granted FDA approval for dosing every two months on February 01, 2022 [L40084] and without the need for an oral lead-in

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: REKAMBYS® 300 MG/ML SUSPENSIÓN INYECTABLE DE LIBERACIÓN PROLONGADA
  4. Drug

    Cefaclor

    go.drugbank.com/drugs/DB00833
    ApprovedInvestigational

    Semisynthetic, broad-spectrum antibiotic derivative of cephalexin.

    Synonyms: 3-Chloro-7-D-(2-phenylglycinamido)-3-cephem-4-carboxylic acidProducts: CEFACLOR RATIO 500MG KAP, Nu-cefaclor
  5. Drug

    Rabeprazole

    go.drugbank.com/drugs/DB01129
    ApprovedInvestigational

    Rabeprazole is an antiulcer drug in the class of proton pump inhibitors. It is a prodrug - in the acid environment of the parietal cells it turns into active sulphenamide form.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InducersProducts: Ag-rabeprazole, Rabeprazole Sodium DR
  6. Drug

    Hydrotalcite

    go.drugbank.com/drugs/DB13322
    ApprovedInvestigationalWithdrawn

    Products: ALKA - SELTZER RA REGULADOR DE ACIDEZ - SUSPENSION, ALKA SELTZER RA REGULADOR DE ACIDEZ TABLETAS MASTICABLES
  7. Drug

    Moxifloxacin

    go.drugbank.com/drugs/DB00218
    ApprovedInvestigational

    Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride) under the brand name Avelox (in some countries also Avalox) for oral treatment.

    Mixtures: Dex-Moxi PF, DexMoxiKetor PFCategories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 Enzyme Inhibitors
  8. Drug

    Amphotericin B

    go.drugbank.com/drugs/DB00681
    ApprovedInvestigational

    Amphotericin B shows a high order of in vitro activity against many species of fungi. Histoplasma capsulatum, Coccidioides immitis, Candida species, Blastomyces dermatitidis, Rhodotorula, Cryptococcus neoformans, Sporothrix schenckii, Mu...

    Products: AMBISOME FOR INJECTION 50 mg/vial
  9. Drug

    Donepezil

    go.drugbank.com/drugs/DB00843
    ApprovedInvestigational

    In 2016, the global burden of dementia was estimated to be 43.8 million, demonstrating a significant increase from a global prevalence of 20.2 million in 1990. Donepezil, also known as Aricept, is a piperidine derivative acetylcholineste...

    Mixtures: EUTEBROL-DUOCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  10. Drug

    Cefixime

    go.drugbank.com/drugs/DB00671
    ApprovedInvestigational

    [L49293] The beta-lactam ring of cefixime inhibits bacterial cell wall synthesis by binding to the penicillin-binding proteins which will then result in lysis. … [A232920, A232925, A232930] Cefixime is a broad-spectrum antibiotic and an orally-active third-generation semisynthetic cephalosporin.

    Products: CEFIXIMA HEXAL AG, SUPRAX DT 400MG DAĞILABİLİR TABLET, 5 ADET