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INO-4800
go.drugbank.com/drugs/DB15693Investigational[A214475, A214478] Follow up studies in both BALB/c mice and Hartley guinea pigs demonstrated the ability of INO-4800 to induce both humoral and T cell-mediated immunity against SARS-CoV-2, including in … [A214475] A Phase 1 clinical trial for INO-4800 in the U.S. (NCT04336410) was started on April 3, 2020, with an expected completion date of July 2021.
Categories: Amino Acids, Peptides, and ProteinsSynonyms: INO-4800 DNA Coronavirus VaccineDental Mesenchymal Pulp Stem Cells
go.drugbank.com/drugs/DB15737InvestigationalDPSCs have multiple properties, and express surface antigens like CD90, CD29, and CD105 but not CD14 or CD45. … DPSCs can remain stable in media once extracted, and have a high proliferation and regeneration capacity.
Remikiren
go.drugbank.com/drugs/DB00212ExperimentalRemikiren is an orally active, high specificity renin inhibitor.
Categories: Agents Acting on the Renin-Angiotensin SystemDelorazepam
go.drugbank.com/drugs/DB01511IllicitInvestigationalIt may have adverse effects such as drowsiness, and cognitive impairments such as short term memory impairment. Delorazepam is an active metabolite of the benzodiazepine known as cloxazolam. … Delorazepam is a benzodiazepine which, like other drugs in its class, possesses anxiolytic, skeletal muscle relaxant, hypnotic and anticonvulsant properties.
Categories: Benzodiazepines and benzodiazepine derivativesInternational brands: ENPegargiminase
go.drugbank.com/drugs/DB06592InvestigationalPegargiminase is an anticancer agent.
Categories: Enzymes and Coenzymes, Compounds used in a research, industrial, or household settingRufinamide
go.drugbank.com/drugs/DB06201ApprovedRufinamide is a triazole derivative and an anticonvulsant medication to treat seizure disorders like Lennox-Gastuat syndrome, a form of childhood epilepsy. … Clinical trials suggest its efficacy in the treatment of partial seizures.
Ceftibuten
go.drugbank.com/drugs/DB01415ApprovedInvestigationalIt is typically used to treat acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial otitis media, pharyngitis, and tonsilitis. … Ceftibuten is a third-generation cephalosporin antibiotic that is orally-administered.
Droloxifene
go.drugbank.com/drugs/DB15641ExperimentalDroloxifene may have an effect on bone and breast tissue because it induces apoptosis. … Droloxifene has an anti-implantation effect in rats, and the effect appears to be not completely due to its anti-estrogenic activity.[L34184]
Categories: Hormones, Hormone Substitutes, and Hormone Antagonists, Compounds used in a research, industrial, or household settingButobarbital
go.drugbank.com/drugs/DB01353ApprovedIllicitButobarbital is a sedative and a hypnotic drug.
Categories: Hypnotics and SedativesCGC-11047
go.drugbank.com/drugs/DB05722InvestigationalCGC-11047 is a polyamine analog designed to halt cell growth and induce apoptosis.