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Reslizumab
go.drugbank.com/drugs/DB06602ApprovedInvestigationalReslizumab is a humanized interleukin-5 (IL-5) antagonist monoclonal antibody (IgG4 kappa) that is produced by recombinant DNA technology in murine myeloma non-secreting 0 (NS0) cells. … It is injected once every four weeks via intravenous infusion. Cinqair is indicated as an add-on maintenance therapy for adults with severe asthma with an eosinophilic phenotype.
ZD4407
go.drugbank.com/drugs/DB06539ExperimentalIt entered Phase 1 clinical trials for chronic obstructive pulmonary disease (COPD) in the United Kingdom but was discontinued during this phase in March 2003
Sovleplenib
go.drugbank.com/drugs/DB17557InvestigationalIt is under investigation in clinical trial NCT03483948 (Phase I Study of Hmpl-523+azacitidine in Elderly Patients With Acute Myeloid Leukemia).
Nitroxoline
go.drugbank.com/drugs/DB01422ExperimentalIt is a hydroxyquinoline derivative unrelated to other classes of drugs.[A179251] Nitroxoline is active against bacterial gyrases.
5-imino-4-(3-trifluoromethyl-phenylazo)-5H-pyrazol-3-ylamine
go.drugbank.com/drugs/DB08666ExperimentalThese are aromatic compounds containing at least one benzene ring. This drug targets the protein methionine aminopeptidase.
Dacetuzumab
go.drugbank.com/drugs/DB12589InvestigationalIt is a humanized anti-CD40 antibody and induces cytotoxicity in human multiple myeloma cells.
AI-850
go.drugbank.com/drugs/DB05842ExperimentalAI-850 is a Cremophor(R)-free formulation of paclitaxel, the active ingredient in Taxol(R), a product used to treat a variety of solid tumors.
Galidesivir
go.drugbank.com/drugs/DB11676Investigational[L12042] Because of its activity against other coronaviruses, it may be studied as a potential therapy for COVID-19. … [L12084] _In vitro_, it displayed broad-spectrum antiviral activity against various negative- and positive-sense RNA viruses,[A191622] including coronaviruses, filoviruses, and arenaviruses.