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Displaying results 5431 - 5440 of 10000 in total
  1. Drug

    Bafilomycin A1

    go.drugbank.com/drugs/DB06733
    Experimental

    The most commonly utilized bafilomycin is bafilomycin A1. This is a useful tool as it can prevent the re-acidification of synaptic vesicles once they have undergone exocytosis. … These compounds all appear in the same fermentation and have similar biological activity. Bafilomycins are specific inhibitors of vacuolar-type H+-ATPase. (V-ATPase).

  2. Drug

    MLN576

    go.drugbank.com/drugs/DB06517
    Experimental

    XR11576 (MLN576) is a novel monophenazine with a mechanism of action that includes interaction with both topoisomerase (Topo) I and II.[A234609]

    Categories: Topoisomerase I Inhibitors, Topoisomerase II Inhibitors
  3. Drug

    Diflorasone

    go.drugbank.com/drugs/DB00223
    Approved

    Diflorasone is a topical corticosteroid used to treat itching and inflammation of the skin.

    Categories: Corticosteroid Hormone Receptor Agonists
  4. Drug

    Amcinonide

    go.drugbank.com/drugs/DB00288
    Approved

    Amcinonide is a corticosteroid.

    Categories: Corticosteroid Hormone Receptor Agonists
  5. Drug

    TSHA-105

    go.drugbank.com/drugs/DB18328
    Investigational

    TSHA-105 is an adeno-associated virus serotype 9 (AAV9) vector with an engineered transgene encoding the human SLC13A5 protein.

  6. Drug

    Pegvisomant

    go.drugbank.com/drugs/DB00082
    ApprovedInvestigational

    Pegvisomant is a highly selective growth hormone (GH) receptor antagonist. It is used to treat acromegaly. … Unlike dopamine or somatostatin analogs (which inhibit growth hormone secretion), this drug actually blocks the hepatic (GH-mediated) production of insulin like growth factor (IGF-1), which is the main

    Categories: Growth Hormone Receptor Antagonist, Growth Hormone Receptor Antagonists
  7. Drug

    Rosemary

    go.drugbank.com/drugs/DB14272
    Investigational

    Rosemary is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

  8. Drug

    Abetimus

    go.drugbank.com/drugs/DB06662
    Investigational

    Abetimus was developed by La Jolla Pharmaceuticals as an immunosuppressant but was never marketed in American or Europe despite application for marketing authorization in the mid-2000s.

  9. Drug

    Etynodiol

    go.drugbank.com/drugs/DB13866
    Experimental

    Etynodiol (INN), or ethynodiol (BAN) is a steroidal progestin related to norethisterone which was never marketed. … While etynodiol is sometimes used as a synonym for etynodiol diacetate, it usually refers to etynodiol diacetate (see [DB00823]), not etynodiol.

  10. Drug

    D-JNKI-1

    go.drugbank.com/drugs/DB05660
    Investigational

    A synthetic, cell permeable peptide that blocks the MAPK-JNK signal pathway; has potential therapeutic value for long-term protection of both the morphological integrity and physiological function of the organ of Corti during times of ox...