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Dihydroergocristine
go.drugbank.com/drugs/DB13345Approved[L2637] It is a semisynthetic ergot alkaloid and thus, it is characterized by a structural skeleton formed by an alkaloid ergoline.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesMosapride
go.drugbank.com/drugs/DB11675InvestigationalMosapride is under investigation for the treatment and prevention of Postoperative Ileus and Gastric Peroral Endoscopic Pyloromyotomy (G-POEM). … Mosapride has been investigated for the treatment and diagnostic of Constipation, Type 2 Diabetes, Functional Dyspepsia, Functional Constipation, and Epigastric Pain Syndrome, among others.
Categories: Drugs for Functional Gastrointestinal Disorders, Serotonin Receptor AgonistsLatrunculin A
go.drugbank.com/drugs/DB02621InvestigationalLatrunculin A is an actin binding macrolide purified from the red sea sponge Latrunculia magnifica. It is under investigation for the treatment of cancer.
Autologous peripheral blood-derived CD34+ cells
go.drugbank.com/drugs/DB16367ApprovedInvestigational[L27741] It is also a cell therapy being investigated by Caladrius Biosciences in the clinical trial NCT04522817 (CLBS119 for Repair of COVID-19 Induced Pulmonary Damage).
Dichloralphenazone
go.drugbank.com/drugs/DB01495ApprovedIllicitIt is typically found in combination products Nodolor and Midrin containing [isometheptene] and [acetaminophen] used for the relief of tension and vascular headaches.
RGX-111
go.drugbank.com/drugs/DB17632InvestigationalDeveloped by REGENXBIO Inc., it was investigated for the treatment of mucopolysaccharidosis Type I (MPS I).[L46666] … RGX-111 is an adeno-associated virus vector AAV9 designed to deliver the α-L-iduronidase (IDUA) gene.
Metribolone
go.drugbank.com/drugs/DB02998ExperimentalIt binds strongly to the androgen receptor and has therefore also been used as an affinity label for this receptor in the prostate and in prostatic tumors.
HGTV-43
go.drugbank.com/drugs/DB05807ExperimentalHGTV43 is an anti-sense treatment designed to produce T cells that are genetically resistant to HIV infection.
RGN6024
go.drugbank.com/drugs/DB33059ExperimentalIt is designed as an orally administered, blood-brain barrier penetrant therapy for brain cancers, especially glioblastoma. … Reglagene announced FDA orphan drug designation for glioblastoma in 2024. RGN6024 remains investigational and is not an approved drug.
Trestolone
go.drugbank.com/drugs/DB05830InvestigationalTrestolone (7α-methyl-19-nortestosterone) is a synthetic androgen developed by the Population Council as a potential candidate drug for use in hormonal male contraceptive methods.
Categories: Hormonal Contraceptives for Systemic Use