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Displaying results 541 - 550 of 10000 in total
  1. Drug

    Levomenthol

    go.drugbank.com/drugs/DB00825
    ApprovedInvestigational

    Forming clear or white waxy, crystalline substance, menthol is typically solid at room temperature. (-)-Menthol is the naturally-occurring and main form of menthol, and is assigned the (1R,2S,5R) configuration … Menthol is a covalent organic compound made synthetically or obtained from peppermint or other mint oils.

    Mixtures: SEE FULL OIL, X-seb T Plus Conditioning ShampooSynonyms: (-)-(1R,3R,4S)-MENTHOL, (−)-(1R,3R,4S)-menthol
  2. Drug

    Clarithromycin

    go.drugbank.com/drugs/DB01211
    ApprovedInvestigational

    Clarithromycin, a semisynthetic macrolide antibiotic derived from erythromycin, inhibits bacterial protein synthesis by binding to the bacterial 50S ribosomal subunit. Binding inhibits peptidyl transferase activity and interferes with am...

    Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: KLARICID® UD, Maclar 500 Clarithromycin Tablets USP 500mg
  3. Drug

    Demplatin pegraglumer

    go.drugbank.com/drugs/DB14807
    Investigational

    Demplatin pegraglumer is under investigation in clinical trial NCT02043288 (Combination Therapy With NC-6004 and Gemcitabine Versus Gemcitabine Alone in Pancreatic Cancer).

    Synonyms: A micelle drug formulation composed of cisplatin and mPEG-poly(l-Glu) diblock copolymer with 1,3-propanediyl linkagecisplatin is incorporated in polymeric micelles via polymer-metal complex formation with
  4. Drug

    Cyclophosphamide

    go.drugbank.com/drugs/DB00531
    ApprovedInvestigational

    Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the liver to form the active aldophosphamide. It has been used in the treatment of lymphoma and leukemia. Its side effect, a...

    Synonyms: (RS)-CyclophosphamideProducts: Cyclophosphamide for Injection USP
  5. Drug

    Anastrozole

    go.drugbank.com/drugs/DB01217
    ApprovedInvestigational

    compared to earlier estrogen receptor modulators such as [tamoxifen]. … [A186877,A186955] Anastrozole was first approved for use in the United States in 1995.[L8863]

    Products: ANABREZ ANASTROZOLE FILM COATED TABLET USP 1MG
  6. Drug

    Narsoplimab

    go.drugbank.com/drugs/DB16418
    ApprovedInvestigational

    [A241030, A241040] Narsoplimab (OMS721), a human IgG4λ anti-MASP-2 antibody, is under consideration as a treatment for hematopoietic stem cell transplant-associated TMA (HSCT-TMA/TA-TMA) and IgA nephropathy … [A241045, A241050] Approved by the FDA on December 24, 2025, narsoplimab-wuug is indicated for the treatment of hematopoietic stem cell transplant–associated thrombotic microangiopathy (TA-TMA) in adults

  7. Drug

    Nimesulide

    go.drugbank.com/drugs/DB04743
    ApprovedWithdrawn

    Nimesulide is a relatively COX-2 selective, non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties.

    Categories: Antiinflammatory Preparations, Non-Steroids for Topical UseProducts: UL-FLAM
  8. Drug

    Amitriptyline

    go.drugbank.com/drugs/DB00321
    ApprovedInvestigational

    Amitriptyline is a tricyclic antidepressant that has been used to treat depression for decades. ELAVIL, a previously approved branded product of amitriptyline, was first approved by the FDA in 1961.

    Mixtures: Limbitrol DSProducts: Amitriptyline Hydrochloride Tablets USP
  9. Drug

    Sulbutiamine

    go.drugbank.com/drugs/DB13416
    Investigational

    Although its clinical efficacy is not yet defined, sulbutiamine is used to treat asthenia. … Sulbutiamine is a synthetic derivative of thiamine (vitamin B1) under the market name Arcalion that is composed of two modified thiamine molecules to form a dimer.

    Categories: Vitamin B ComplexProducts: NEURO UP® TABLETAS CUBIERTA CON PELICULA 200 MG
  10. Drug

    Calcitriol

    go.drugbank.com/drugs/DB00136
    ApprovedInvestigationalNutraceutical

    It is produced in the body after series of conversion steps of 7-dehydrocholesterol from exposure to UV light. 7-dehydrocholesterol is converted to [DB00169] (vitamin D3) in the skin, which is then converted … Calcitriol is an active metabolite of vitamin D with 3 hydroxyl (OH) groups and is commonly referred to as 1,25-dihydroxycholecalciferol, or 1alpha,25-dihydroxyvitamin D<sub>3</sub>, 1,25-dihydroxyvitamin

    Categories: Antipsoriatics for Topical UseSynonyms: (1S,3R,5Z,7E)-9,10-secocholesta-5,7,10-triene-1,3,25-triol, (5Z,7E)-(1S,3R)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol