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Cytochrome b6-f complex subunit 5
go.drugbank.com/bio_entities/BE0003906TargetMastigocladus laminosusPetG is required for either the stability or assembly of the cytochrome b6-f complex. … Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
Polypeptides: Cytochrome b6-f complex subunit 5Synonyms: Cytochrome b6-f complex subunit V, Cytochrome b6-f complex subunit PetGFatty acid oxidation complex subunit alpha
go.drugbank.com/bio_entities/BE0004256TargetPseudomonas fragiInvolved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-Co...
Polypeptides: Fatty acid oxidation complex subunit alphaTrafficking protein particle complex subunit 4
go.drugbank.com/bio_entities/BE0004278TargetHumansCore component of the TRAPP complexes which has a function of guanine nucleotide exchange factor activity for Rab1 GTPase (Probable). … Plays a role in vesicular transport from endoplasmic reticulum to Golgi and autophagy (PubMed:31794024). May play a role in dendrite postsynaptic membrane trafficking (By similarity)
Polypeptides: Trafficking protein particle complex subunit 4Trafficking protein particle complex subunit 1
go.drugbank.com/bio_entities/BE0004279TargetHumansMay play a role in vesicular transport from endoplasmic reticulum to Golgi
Polypeptides: Trafficking protein particle complex subunit 1T-complex protein 1 subunit gamma
go.drugbank.com/bio_entities/BE0004554TargetHumansAs part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia (PubMed:20080638) … Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of actin, tubulin and other proteins upon ATP hydrolysis (PubMed:25467444, PubMed:36493755
Polypeptides: T-complex protein 1 subunit gammaSynonyms: Chaperonin containing T-complex polypeptide 1 subunit 3T-complex protein 1 subunit eta
go.drugbank.com/bio_entities/BE0009220TargetPlasmodium falciparum (isolate 3D7)Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin (By similarity).
Polypeptides: T-complex protein 1 subunit etaH/ACA ribonucleoprotein complex subunit DKC1
go.drugbank.com/bio_entities/BE0012026TargetHumansCatalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA (PubMed:25219674, PubMed:32554502).
Polypeptides: H/ACA ribonucleoprotein complex subunit DKC1Bupropion
go.drugbank.com/drugs/DB01156ApprovedInvestigationalMore specifically, bupropion binds to the norepinephrine transporter (NET) and the dopamine transporter (DAT). … [A6399,A178840] Lack of activity at these receptors results in a more tolerable side effect profile; bupropion is less likely to cause sexual side effects, sedation, or weight gain as compared to SSRIs
Choriogonadotropin alfa
go.drugbank.com/drugs/DB00097ApprovedInvestigational-121, SER-127, SER-132 and SER-138 (on beta subunit). … human chorionic gonadotropin with 2 subunits, alpha = 92 residues, beta = 145 residues, each with N-and O-linked carbohydrate moieties linked to ASN-52 and ASN-78 (on alpha subunit) and ASN-13, ASN-30, SER
Categories: Genito Urinary System and Sex Hormones, Sex Hormones and Modulators of the Genital SystemPixantrone
go.drugbank.com/drugs/DB06193ApprovedWithdrawnIt will compare pixantrone efficacy to that of gemcitabine. [2]