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Displaying results 541 - 550 of 5300 in total
  1. Drug

    Phenindione

    go.drugbank.com/drugs/DB00498
    ApprovedInvestigational

    (From Martindale, The Extra Pharmacopoeia, 30th ed, p234) … An indandione that has been used as an anticoagulant. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higher incidence of severe adverse effects.

  2. Drug

    Glyburide

    go.drugbank.com/drugs/DB01016
    ApprovedInvestigational

    Glyburide is a second generation sulfonylurea used to treat patients with diabetes mellitus type II. It is typically given to patients who cannot be managed with the standard first line therapy, metformin. Glyburide stimulates insulin se...

  3. Drug

    Tacrolimus

    go.drugbank.com/drugs/DB00864
    ApprovedInvestigational

    Tacrolimus (also FK-506 or Fujimycin) is an immunosuppressive drug whose main use is after organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection.

    Products: TACROLIMUS EG
  4. Drug

    Metamizole

    go.drugbank.com/drugs/DB04817
    ApprovedInvestigationalWithdrawn

    [A251805] Metamizole is still used in certain countries in Europe, Asia and South America.[A251805]

    Mixtures: NEURALGIN RXProducts: NEURALGIN RX, DIPIRONA X 1 G / 2MLSOLUCION INYECTABLE
  5. Drug

    Topiramate

    go.drugbank.com/drugs/DB00273
    ApprovedInvestigational

    Topiramate is a anti-epileptic drug used to manage seizures and prevent migraines. It was initially approved by the FDA in 1996. In 2004, topiramate was approved for the prevention of migraine in adults. Since 2012, the extended-release ...

    Products: TOPIRAMATO EG, Ran-topiramate
  6. Indication

    Severe Alopecia Areata (AA)

    go.drugbank.com/conditions/DBCOND0158827
    Drugs: Deuruxolitinib · Ritlecitinib
    Synonyms: Severe Alopecia Areata (AA)
  7. Drug

    Pregabalin

    go.drugbank.com/drugs/DB00230
    ApprovedInvestigational

    Pregabalin is structurally similar to gamma-aminobutyric acid (GABA) - an inhibitory neurotransmitter.

    Products: PREGABALIN EG, EPIBALIN ER 330 MG
  8. Drug

    Nirmatrelvir

    go.drugbank.com/drugs/DB16691
    ApprovedInvestigational

    Nirmatrelvir (PF-07321332) is an orally bioavailable 3C-like protease (3CL<sup>PRO</sup>) inhibitor that is the subject of clinical trial NCT04756531. … [L33359] In December 2021, the FDA granted an emergency use authorization to Paxlovid, a co-packaged product containing both nirmatrelvir and [ritonavir], for the treatment of certain patients with

  9. Drug

    Butriptyline

    go.drugbank.com/drugs/DB09016
    ApprovedWithdrawn

    Butriptyline is a tricyclic antidepressant which has been used in Europe since 1974. It is the isobutyl side chain homologue of amitriptyline.

  10. Drug

    Betahistine

    go.drugbank.com/drugs/DB06698
    ApprovedInvestigational

    Ménière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing loss. It has a significant impact on both the physical and social functioning of affected individuals. Betahistine is a histamine...

    Products: BETAISTINA EG