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Displaying results 5491 - 5500 of 10000 in total
  1. Drug

    Iodide I-131

    go.drugbank.com/drugs/DB09293
    ApprovedInvestigational

    Iodide I-131 (as Sodium iodide I-131) is a radioisotopic drug used for the treatment and palliation of thyroid malignancy. … For this reason, less toxic iodine isotopes such as I-123 are more frequently used in nuclear imaging, while I-131 is reserved for its tissue destroying effects.

    Salts: Sodium iodide I-131Synonyms: 131 I, 131-I
  2. Drug

    Witch hazel

    go.drugbank.com/drugs/DB11111
    ApprovedInvestigationalNutraceutical

    Mixtures: Preparation H-PE Gel, HAMAZINC KREM ,90 GProducts: HAMETAN% 25 MERHEM, 50 G, Tension No. 5
  3. Drug

    Gallium citrate Ga-67

    go.drugbank.com/drugs/DB06784
    Approved

    Although the mechanism is unknown, gallium Ga 67 concentrates in lysosomes and is bound to a soluble intracellular protein in certain viable primary and metastatic tumors and focal sites of inflammation

    Products: MON.GALYUM-67 74 MBQ/ML IV ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 ADET (5 ML), GA - 67 MM-1
  4. Drug

    CHIR-124

    go.drugbank.com/drugs/DB06852
    Experimental

    CHIR-124 is a potent inhibitor of Chk1 that potentiates the cytotoxicity of topoisomerase I poisons in vitro and in vivo.

    Categories: Heterocyclic Compounds, 2-Ring
  5. Target

    NADH-ubiquinone oxidoreductase chain 5

    go.drugbank.com/bio_entities/BE0000580
    TargetHumans

    Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor (PubMed:15250827). Essential ...

    Polypeptides: NADH-ubiquinone oxidoreductase chain 5Synonyms: NADH dehydrogenase subunit 5
  6. Target

    C-C motif chemokine 5

    go.drugbank.com/bio_entities/BE0000975
    TargetHumans

    Recombinant RANTES protein induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).

    Polypeptides: C-C motif chemokine 5
  7. Target

    Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial

    go.drugbank.com/bio_entities/BE0001205
    TargetHumans

    Catalyzes the cleavage of 2'-deoxyuridine 5'-triphosphate (dUTP) into 2'-deoxyuridine 5'-monophosphate (dUMP) and inorganic pyrophosphate and through its action efficiently prevents uracil misincorporation

    Polypeptides: Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial
  8. Target

    Fatty acid-binding protein 5

    go.drugbank.com/bio_entities/BE0001984
    CarrierTargetHumans

    Intracellular carrier for long-chain fatty acids and related active lipids, such as endocannabinoids, that regulate the metabolism and actions of the ligands they bind. In addition to the cytosolic transport, selectively delivers specifi...

    Polypeptides: Fatty acid-binding protein 5
  9. Target

    5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase

    go.drugbank.com/bio_entities/BE0002007
    TargetEscherichia coli (strain K12)

    Can also use 5'-isobutylthioadenosine, 5'-n-butylthioadenosine, S-adenosyl-D-homocysteine, decarboxylated adenosylhomocysteine, deaminated adenosylhomocysteine and S-2-aza-adenosylhomocysteine as substrates … Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.

    Polypeptides: 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidaseSynonyms: 5'-deoxyadenosine nucleosidase, 5'-methylthioadenosine nucleosidase
  10. Target

    Proteasome subunit beta type-5

    go.drugbank.com/bio_entities/BE0002348
    TargetHumans

    Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associat...

    Polypeptides: Proteasome subunit beta type-5Synonyms: beta-5, Proteasome subunit beta-5