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Displaying results 5511 - 5520 of 10000 in total
  1. Target

    5'-AMP-activated protein kinase

    go.drugbank.com/bio_entities/BE0011011
    TargetRat

    Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism (PubMed:14511394). In response to reduction of intracellular ATP levels, AMPK activa...

    Polypeptides: 5'-AMP-activated protein kinase subunit beta-2, 5'-AMP-activated protein kinase catalytic subunit alpha-2Synonyms: 5'-AMP-activated protein kinase 40 kDa subunit, AMPK subunit alpha-2
  2. Target

    Inosine-5'-monophosphate dehydrogenase 1

    go.drugbank.com/bio_entities/BE0000761
    TargetEnzymeHumans

    Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays

    Polypeptides: Inosine-5'-monophosphate dehydrogenase 1
  3. Target

    Glutamate receptor ionotropic, kainate 5

    go.drugbank.com/bio_entities/BE0000828
    TargetHumans

    Ionotropic glutamate receptor that functions as a cation-permeable ligand-gated ion channel, gated by L-glutamate and the glutamatergic agonist kainic acid. Cannot form functional channels on its own and produces channel activity only in...

    Polypeptides: Glutamate receptor ionotropic, kainate 5Synonyms: Glutamate receptor KA-2, Excitatory amino acid receptor 2
  4. Target

    DNA (cytosine-5)-methyltransferase 1

    go.drugbank.com/bio_entities/BE0000892
    TargetHumans

    DNA methyltransferase that methylates CpG residues (PubMed:17200670, PubMed:18754681, PubMed:21745816, PubMed:26070743). Preferentially methylates hemimethylated DNA (PubMed:21745816, PubMed:26070743). Associates with DNA replication sit...

    Polypeptides: DNA (cytosine-5)-methyltransferase 1Function: DNA (cytosine-5-)-methyltransferase activity
  5. Target

    N-(5'-phosphoribosyl)anthranilate isomerase

    go.drugbank.com/bio_entities/BE0001549
    TargetThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)

    Polypeptides: N-(5'-phosphoribosyl)anthranilate isomerase
  6. Target

    Ribose-5-phosphate isomerase A

    go.drugbank.com/bio_entities/BE0001628
    TargetShigella flexneri

    Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.

    Polypeptides: Ribose-5-phosphate isomerase AFunction: ribose-5-phosphate isomerase activity
  7. Target

    Pyridoxine/pyridoxamine 5'-phosphate oxidase

    go.drugbank.com/bio_entities/BE0002066
    TargetEscherichia coli (strain K12)

    Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).

    Polypeptides: Pyridoxine/pyridoxamine 5'-phosphate oxidaseSynonyms: Pyridoxal 5'-phosphate synthase
  8. Target

    Glutathione S-transferase Mu 5

    go.drugbank.com/bio_entities/BE0002285
    TargetEnzymeHumans

    Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles

    Polypeptides: Glutathione S-transferase Mu 5Synonyms: GSTM5-5, GST class-mu 5
  9. Target

    Sphingosine 1-phosphate receptor 5

    go.drugbank.com/bio_entities/BE0002432
    TargetHumans

    Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/0)alpha and G(12) subclass of h...

    Polypeptides: Sphingosine 1-phosphate receptor 5Synonyms: S1P receptor 5
  10. Target

    Neuropeptide Y receptor type 5

    go.drugbank.com/bio_entities/BE0002452
    TargetHumans

    Receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Seems to be associated with food intake. Could be involved in feeding disorders

    Polypeptides: Neuropeptide Y receptor type 5