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Displaying results 5521 - 5530 of 10000 in total
  1. Target

    Keratin-associated protein 5-3

    go.drugbank.com/bio_entities/BE0004472
    TargetHumans

    In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through ...

    Polypeptides: Keratin-associated protein 5-3Synonyms: Keratin-associated protein 5-9
  2. Target

    DNA (cytosine-5)-methyltransferase 3A

    go.drugbank.com/bio_entities/BE0009880
    TargetHumans

    May preferentially methylate DNA linker between 2 nucleosomal cores and is inhibited by histone H1 (By similarity). Plays a role in paternal and maternal imprinting (By similarity).

    Polypeptides: DNA (cytosine-5)-methyltransferase 3A
  3. Target

    Dual specificity protein phosphatase 5

    go.drugbank.com/bio_entities/BE0010466
    TargetHumans

    Dual specificity protein phosphatase; active with phosphotyrosine, phosphoserine and phosphothreonine residues. The highest relative activity is toward ERK1

    Polypeptides: Dual specificity protein phosphatase 5
  4. Target

    Transcriptional enhancer factor TEF-5

    go.drugbank.com/bio_entities/BE0018748
    TargetHumans

    The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1

    Polypeptides: Transcriptional enhancer factor TEF-5
  5. Target

    Ribitol 5-phosphate transferase FKRP

    go.drugbank.com/bio_entities/BE0019722
    TargetHumans

    Catalyzes the transfer of a ribitol 5-phosphate from CDP-L-ribitol to the ribitol 5-phosphate previously attached by FKTN/fukutin to the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta … This constitutes the second step in the formation of the ribose 5-phosphate tandem repeat which links the phosphorylated O-mannosyl trisaccharide to the ligand binding moiety composed of repeats of 3-xylosyl-alpha

    Polypeptides: Ribitol 5-phosphate transferase FKRPSynonyms: Ribitol-5-phosphate transferase
  6. Drug

    Mannitol

    go.drugbank.com/drugs/DB00742
    ApprovedInvestigational

    As a result, cerebral edema, elevated intracranial pressure, and cerebrospinal fluid volume and pressure may be reduced. … Mannitol may also be used for the promotion of diuresis before irreversible renal failure becomes established; the promotion of urinary excretion of toxic substances; as an Antiglaucoma agent; and as a

    Synonyms: D-Mannitol, D-(-)-MannitolInternational brands: Mannisol A
  7. Drug

    Triclocarban

    go.drugbank.com/drugs/DB11155
    Approved

    It is a bacteriostatic compound that has been found in antibacterial soaps and other personal care products. … In 2017, the US FDA prohibited the marketing of over-the-counter (OTC) consumer antiseptic wash products containing triclocarban due to negative health effects such as bacterial resistance or hormonal

    Synonyms: 1-(3',4'-dichlorophenyl)-3-(4'-chlorophenyl)urea, N-(4-chlorophenyl)-N'-(3,4-dichlorophenyl)ureaProducts: DG Body Antibacterial Deodorant 3.5 oz bar, Clearskin 2 Cleansing Cake 1.5%
  8. Drug

    Hexoprenaline

    go.drugbank.com/drugs/DB08957
    ApprovedWithdrawn

    Hexoprenaline is a stimulant of beta 2 adrenergic receptors. It is used as a bronchodilator, antiasthmatic, and tocolytic agent.

    Categories: Adrenergic beta-2 Receptor Agonists, Selective Beta 2-adrenergic AgonistsProducts: Gynipral 10 µg/2 ml - Ampullen, Gynipral 25 µg - Konzentrat zur Infusionsbereitung
  9. Drug

    Iluzanebart

    go.drugbank.com/drugs/DB18275
    Investigational

    Synonyms: Immunoglobulin G1 [296-cysteine,301-glycine,306-cysteine], anti-(human triggering receptor expressed on myeloid cells 2) (human monoclonal VGL101 γ1-chain), disulfide with human monoclonal VGL101 κ-chain, gamma1 heavy chain Homo sapiens (1-451) [VH (Homo sapiens IGHV5-51*01 (96.9%) -(IGHD) -IGHJ1*01 (100%), CDR-IMGT [8.8.14] (26-33.51-58.97-110)) (1-121) -Homo sapiens IGHG1*03v, G1m3>G1m17, nG1m1 CH1 K120
  10. Drug

    Azelaic acid

    go.drugbank.com/drugs/DB00548
    ApprovedInvestigational

    Azelaic acid is effective against a number of skin conditions, such as mild to moderate acne, when applied topically in a cream formulation of 20%. … Azelaic acid is a saturated dicarboxylic acid found naturally in wheat, rye, and barley.

    Mixtures: 2% Salicylic Acid FACIAL CLEANSER, Azelaic Acid 15% / Niacinamide 4%Synonyms: n-nonanedioic acid