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Dabigatran etexilate
go.drugbank.com/drugs/DB06695ApprovedInvestigationalDabigatran etexilate is an oral prodrug that is hydrolyzed to the competitive and reversible direct thrombin inhibitor dabigatran. Dabigatran etexilate may be used to decrease the risk of venous thromboembolic events in patients in whom ...
Categories: Heterocyclic Compounds, 2-Ring, P-glycoprotein substratesProducts: PRADAXA® 150 MG, DABITROM® 150Binimetinib
go.drugbank.com/drugs/DB11967ApprovedInvestigationalBinimetinib, also known as _Mektovi_, is a potent and selective oral mitogen-activated protein kinase 1/2 (MEK 1/2) inhibitor which is combined with [Encorafenib]. … [A34275,L3335] On June 27, 2018, the Food and Drug Administration approved the combination of [Encorafenib] and binimetinib (BRAFTOVI and MEKTOVI, from Array BioPharma Inc.) in combination for patients
Categories: Heterocyclic Compounds, 2-Ring, MAP Kinase Kinase 2, antagonists & inhibitorsProducts: MEKTOVI® 15 MG TABLETAS RECUBIERTAS, Mektovı 15 mg Film Kaplı Tablet, 84 ADETPonatinib
go.drugbank.com/drugs/DB08901ApprovedInvestigationalPonatinib is a novel Bcr-Abl tyrosine kinase inhibitor that is especially effective against the T315I mutation for the treatment of chronic myeloid leukemia. FDA approved on December 14, 2012.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic IndexProducts: ICLUSIG® 15 MG TABLETAS RECUBIERTAS, ICLUSIG TABLET 45 MGSaccharin
go.drugbank.com/drugs/DB12418InvestigationalSaccharin has been investigated for the treatment of Hypertension and Hyperglycemia.
Categories: Heterocyclic Compounds, 2-Ring, Heterocyclic Compounds, 1-RingProducts: DULCARYL EFERVESAN TABLET 1/2 DOZ, 100 ADET, DULCARYL EFERVESAN TABLET 1/2 DOZ, 1000 ADETOctasulfur
go.drugbank.com/drugs/DB09353ApprovedSulfur is a chemical element that is present in all living tissues. The most commonly used form of pharmaceutical sulfur is Octasulfur (S8).
Mixtures: NW SULPHUR 2%W/W AND SALICYLIC ACID 2%W/W CREAM, Clearskin 2 Tinted Blemish CrmProducts: Postacne Lotion 2%, Postacne Lotion - 2%Glycerin
go.drugbank.com/drugs/DB09462ApprovedInvestigationalA trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism.
Mixtures: 2% Salicylic Acid FACIAL CLEANSER, Aqua Collagen Solu Tion Marine Hydroge L Eye Crea M MaskCategories: Cytochrome P-450 CYP2E1 Inducers, Cytochrome P-450 Enzyme InducersCapsaicin
go.drugbank.com/drugs/DB06774ApprovedInvestigationalCapsaicin is a naturally-occurring botanical irritant in chili peppers, synthetically derived for pharmaceutical formulations. … The most recent capsaicin FDA approval was Qutenza, an 8% capsaicin patch dermal-delivery system, indicated for neuropathic pain associated with post-herpetic neuralgia.
Mixtures: Dfs 1.5%/ms 25%/menth 6%/cap 0.025% Pak, DFS 75mg DR/MS 25%/MENTH 6%/CAP 0.025% PAKCategories: Cytochrome P-450 Substrates, Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substratesConjugated estrogens
go.drugbank.com/drugs/DB00286ApprovedInvestigationalsulfate, 3% of equilenin sulfate, 5% of 17-alpha and 17-beta-dihydroequilenin sulfate, 2% of 17-alpha-estradiolsulfate and 3% of 17-beta-estradiolsulfate. … [L5605, T475] The conjugated estrogen product contains a mix of estrogen from which about 50% is represented by estrone sulfate followed by 25% of equilin sulfate, 15% of 17-alpha-dehydroequilenin
Mixtures: DUAVİVE 0.45 MG/20 MG DEĞİŞTİRİLMİŞ SALIMLI TABLET, 28 TABLET, DUAVIVE 20 mg/0.45 mg modified - release tabletsCategories: Cytochrome P-450 Substrates, P-glycoprotein substratesEtonogestrel
go.drugbank.com/drugs/DB00294ApprovedInvestigationalEtonogestrel molecule is a 3-ketodesogestrel or 19-nortestosterone which is a synthetic biologically active metabolite of progestin desogestrel.
Mixtures: Perlinring 0,120 mg/0,015 mg pro 24 Stunden - Vaginalring, NuvaRing 0,120 mg/0,015 mg pro 24 Stunden - VaginalringCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesFlumethasone
go.drugbank.com/drugs/DB00663ApprovedVet approvedAs it is a privalate salt, its anti-inflammatory action is concentrated at the site of application. … This local effect on diseased areas results in a prompt decrease in inflammation, exudation and itching.
Mixtures: LOCACORTENE VİOFORME 0,2 MG/G+30 MG/G KREM, 15 G, LOCACORTENE VİOFORME 0,2 MG/G+30 MG/G KREM, 30 GCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates