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Displaying results 5571 - 5580 of 10000 in total
  1. Drug

    Sunitinib

    go.drugbank.com/drugs/DB01268
    ApprovedInvestigational

    Sunitinib is a small-molecule multi-targeted receptor tyrosine kinase (RTK) inhibitor. … In addition, sunitinib inhibits other RTKs including RET, CSF-1R, and flt3.

    Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic IndexProducts: SUNITINIB EG, SUNITINIB DR. REDDY'S
  2. Drug

    Losartan

    go.drugbank.com/drugs/DB00678
    ApprovedInvestigational

    [L7423] Angiotensin-converting enzyme (ACE) inhibitors are used for a similar indication but are associated with a cough. … [L7423] Losartan was granted FDA approval on 14 April 1995.[L7423]

    Mixtures: TOZAAR PLUS LS 50/12.5mg Tablet, LOSARTAN E IDROCLOROTIAZIDE DOC GENERICICategories: Agents Acting on the Renin-Angiotensin System
  3. Drug

    Levocetirizine

    go.drugbank.com/drugs/DB06282
    ApprovedInvestigational

    [L7694] Levocetirizine was granted FDA approval in 1995.[L7694] … Levocetirizine is a selective histamine H<sub>1</sub> antagonist used to treat a variety of allergic symptoms.[A181748,A181790,L7694] It is the R enantiomer of [cetirizine].

    Mixtures: NORAVER ® GFAST CAPSULAS BLANDAS CONTRA LOS SINTOMAS DE LA GRIPA, BREATHEZY - LProducts: LEVOCETIRIZINA EG, DG Health Allergy Relief
  4. Drug

    Amoxicillin

    go.drugbank.com/drugs/DB01060
    ApprovedInvestigationalVet approved

    Amoxicillin, or BRL-2333, is a penicillin G derivative first described in the literature in 1972. … [A190648] Amoxicillin was granted FDA approval on 18 January 1974.[L11644]

    Mixtures: BIOMICILINA®POLVO PARA RECONSTITUIR A 100ML DE SUSPENSION ORAL, AMOXICILINA + CLAVULANATO DE POTASIO 400 + 57 MG / 5 ML POLVO PARA RECONSTIUTIR A SUSPENSIÓN ORALProducts: RHAMOXICILINA POLVO PARA RECONSTITUIR A SUSPENSION DE 250 MG/5 ML, AMOXICILLINA E ACIDO CLAVULANICO PFIZER
  5. Drug

    Fluorouracil

    go.drugbank.com/drugs/DB00544
    ApprovedInvestigational

    A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the thymidylate synthetase conversion of deoxyuridylic acid to thymidylic acid.

    Mixtures: Actikerall 5 mg/g + 100 mg/g Lösung zur Anwendung auf der HautCategories: Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2A6 Substrates with a Narrow Therapeutic Index
  6. Drug

    Famotidine

    go.drugbank.com/drugs/DB00927
    ApprovedInvestigational

    disease, famotidine was about 20 to 50 times more potent at inhibiting gastric acid secretion than [cimetidine] and eight times more potent than [ranitidine] on a weight basis. … [L11166] Compared to other H<sub>2</sub> receptor antagonists, famotidine displays high selectivity towards this receptor; in a study consisting of healthy volunteers and patients with acid hypersecretory

    Mixtures: DG Health Dual Action Complete, DG Health acid reducer completeSynonyms: N-Sulfamoyl-3-((2-guanidinothiazol-4-yl)methylthio)propionamide, 3-(((2-((Aminoiminomethyl)amino)-4-thiazolyl)methyl)thio)-N-(aminosulfonyl)propanimidamide
  7. Drug

    Zofenopril

    go.drugbank.com/drugs/DB13166
    ApprovedInvestigational

    Zofenopril is employed as both a cardioprotective and anti-hypertensive agent. It is an angiotensin-converting enzyme (ACE) inhibitor.

    Mixtures: ZOFENOPRIL E IDROCLOROTIAZIDE DOC GENERICI, ZOFENOPRIL E IDROCLOROTIAZIDE EGCategories: Agents Acting on the Renin-Angiotensin System
  8. Target

    Macrophage receptor MARCO

    go.drugbank.com/bio_entities/BE0009001
    TargetHumans

    Pattern recognition receptor (PRR) which binds Gram-positive and Gram-negative bacteria (PubMed:9468508). Also plays a role in binding of unopsonized particles by alveolar macrophages (By similarity). Binds to the secretoglobin SCGB3A2 (...

    Polypeptides: Macrophage receptor MARCO
  9. Drug

    Calcium acetate

    go.drugbank.com/drugs/DB00258
    Approved

    The chemical compound calcium acetate is the calcium salt of acetic acid. It has been commonly referred to as the acetate of lime. The anhydrous form is very hygroscopic, therefore the monohydrate is the common form.

    Mixtures: ACETATO DE ALUMINIO, ACETATO DE ALUMINIO POLVOCategories: Compounds used in a research, industrial, or household setting
  10. Pathway

    De Novo Triacylglycerol Biosynthesis TG(16:0/16:0/18:2(9Z,12Z))

    smpdb.ca/view/SMP0015907
    Metabolic

    (Wikipedia) De novo biosynthesis of triglycerides is also known as the phosphatidic acid pathway, and it is mainly associated with the liver and adipose tissue.

    Drugs: NADH · sn-glycerol 3-phosphate · Dihydroxyacetone phosphate