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Amodiaquine
go.drugbank.com/drugs/DB00613ApprovedInvestigationalA 4-aminoquinoquinoline compound with anti-inflammatory properties.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesImatinib
go.drugbank.com/drugs/DB00619ApprovedInvestigational[A249305] It was deemed a "miracle drug" due to its clinical success, as oncologist Dr. … Imatinib is a small molecule kinase inhibitor that revolutionized the treatment of cancer, particularly chronic myeloid leukemia, in 2001.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesSynonyms: α-(4-methyl-1-piperazinyl)-3'-((4-(3-pyridyl)-2-pyrimidinyl)amino)-p-toluidideTriamcinolone
go.drugbank.com/drugs/DB00620ApprovedInvestigationalVet approved[L8255] Triamcinolone can be used as a one time adjunct treatment of osteoarthritic knee pain,[L8264] or first line as a topical treatment of corticosteroid responsive dermatoses. … [L8246,L8249,L8252,L8255,L8258,L8261,L8264] Triamcinolone was granted FDA approval on 3 December 1957.
Synonyms: 9-fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dioneInternational brands: Omcilon-ANicardipine
go.drugbank.com/drugs/DB00622ApprovedInvestigationalA potent calcium channel blockader with marked vasodilator action.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: NINAX 25 MG/10 ML IV INFÜZYON IÇIN KONSANTRE ÇÖZELTI IÇEREN AMPUL ,1 AMPULTestosterone
go.drugbank.com/drugs/DB00624ApprovedInvestigationalTestosterone is a steroid sex hormone indicated to treat primary hypogonadism and hypogonadotropic hypogonadism.
Categories: 3-Oxoandrosten (4) Derivatives, P-glycoprotein inhibitorsSynonyms: 4-androsten-17β-ol-3-one, 17beta-hydroxy-4-androsten-3-oneNiacin
go.drugbank.com/drugs/DB00627ApprovedInvestigationalNutraceuticalNiacin is a B vitamin used to treat vitamin deficiencies as well as hyperlipidemia, dyslipidemia, hypertriglyceridemia, and to reduce the risk of myocardial infarctions.
Mixtures: Formula F L W, B 6 PlusCategories: Vitamin B Complex, Cytochrome P-450 CYP2D6 InhibitorsClorazepic acid
go.drugbank.com/drugs/DB00628ApprovedIllicitSimilar to other benzodiazepines, the active metabolite of clorazepate enhances the binding of gamma-aminobutyric acid (GABA) to the GABA type A (GABA-A) receptor, which promotes channel opening and neuronal … Clorazepic acid (clorazepate) is a water-soluble benzodiazepine with muscle-relaxant and anticonvulsant actions effective in the treatment of anxiety.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingSynonyms: 7-chloro-2,3-dihydro-2,2-dihydroxy-5-phenyl-1H-1,4-benzodiazepine-3-carboxylic acidClofarabine
go.drugbank.com/drugs/DB00631ApprovedInvestigationalClofarabine is a purine nucleoside antimetabolite that is being studied in the treatment of cancer. It is marketed as Clolar in the U.S. and Canada, or Evoltra in Europe, Australia, and New Zealand. … Clofarabine is used in paediatrics to treat a type of leukaemia called relapsed or refractory acute lymphoblastic leukaemia (ALL), only after at least two other types of treatment have failed.
Categories: Heterocyclic Compounds, 2-Ring, OCT2 Substrates with a Narrow Therapeutic IndexSynonyms: (2R,3R,4S,5R)-5-(6-amino-2-chloropurin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol, 2-chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)adeninePrednisone
go.drugbank.com/drugs/DB00635ApprovedInvestigationalVet approvedA synthetic anti-inflammatory glucocorticoid derived from [cortisone].[A187463] It is biologically inert and converted to [prednisolone] in the liver.
Categories: CHOP-R chemotherapy regimen, P-glycoprotein inducersSynonyms: 1, 2-DehydrocortisoneClofibrate
go.drugbank.com/drugs/DB00636ApprovedWithdrawnA fibric acid derivative used in the treatment of hyperlipoproteinemia type III and severe hypertriglyceridemia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p986)
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersSynonyms: 2-(4-Chlorophenoxy)-2-methylpropanoic acid ethyl ester, 2-(p-Chlorophenoxy)-2-methylpropionic acid ethyl ester