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Nonacog beta pegol
go.drugbank.com/drugs/DB13933ApprovedInvestigationalIt is produced without animal-derived materials and with an attached 40kDa polyethylene glycol (PEG) molecule for peptide activation by a site-directed glycoPEGylation. … Once activated, the activation molecule with PEG is cleaved to leave the activated factor IX (Factor IXa).
Categories: Compounds used in a research, industrial, or household settingSynonyms: Coagulation Factor IX (Recombinant), GlycoPEGylatedMoxifloxacin
go.drugbank.com/drugs/DB00218ApprovedInvestigationalBayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride) under the brand name Avelox (in some countries also Avalox) for oral treatment. … Moxifloxacin is a synthetic fluoroquinolone antibiotic agent.
Mixtures: DROXPAN-DX, TQ OFTAMOX D UD®Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UsePanitumumab
go.drugbank.com/drugs/DB01269ApprovedInvestigationalPanitumumab was granted FDA approval on 27 September 2006.[L17663] … Panitumumab (ABX-EGF) is a recombinant human IgG2 monoclonal antibody that binds specifically to the human epidermal growth factor receptor (EGFR). This drug is an antineoplastic agent.
Products: Vectibix 100mg Concentrate for Solution for Infusion, Vectibix Concentrate for Solution for Infusion 100 mg/vialAnti-inhibitor coagulant complex
go.drugbank.com/drugs/DB13151ApprovedInvestigationalIt is used to control bleeding in hemophilia A and B patients with inhibitors. … Anti-inhibitor coagulant complex, also known as FEIBA (factor eight inhibitor bypassing activity), contains several proteins involved in the prothrombinase complex.
Products: Feiba Nf, FEIBA 500 UFusidic acid
go.drugbank.com/drugs/DB02703ApprovedInvestigationalIt is often used topically in creams and eyedrops but is available in systemic formulations including tablets and injections. … An antibiotic isolated from the fermentation broth of Fusidium coccineum. (From Merck Index, 11th ed) It acts by inhibiting translocation during protein synthesis.
Mixtures: FUCICORT(R), ACELER-COCategories: Antibiotics for Topical Use, Antibacterials for Systemic UseArsenic trioxide
go.drugbank.com/drugs/DB01169ApprovedInvestigationalThe enzyme thioredoxin reductase has recently been identified as a target for arsenic trioxide. … In general, arsenic is known to be a naturally toxic substance capable of eliciting a variety of dangerous adverse effects.
Products: Arsenic Trioxide for Injection, Teva-arsenic Trioxide for InjectionCimetidine
go.drugbank.com/drugs/DB00501ApprovedInvestigationalIt inhibits gastric acid secretion, as well as pepsin and gastrins output. It also blocks the activity of cytochrome P-450 which might explain proposals for use in neoadjuvant therapy. … A histamine congener, it competitively inhibits histamine binding to histamine H2 receptors. Cimetidine has a range of pharmacological actions.
Categories: Drugs for Acid Related Disorders, Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord)Synonyms: N''-cyano-N-methyl-N'-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]thio}ethyl)guanidine, N-cyano-N'-methyl-N''-(2-([(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl)ethyl)guanidineArbutin
go.drugbank.com/drugs/DB11217ApprovedIt has also been used as an anti-infective for the urinary system as well as a diuretic [F43]. … Most commonly, it is an active ingredient in skincare and cosmetic products as a skin-lightening agent for the prevention of melanin formation in various skin conditions that involve cutaneous hyperpigmentation
Mixtures: OHUI White Extreme Illuminating Pact No.10, OHUI White Extreme Illuminating Pact No.10Synonyms: hydroquinone O-β-D-glucopyranoside, Hydroquinone-O-beta-D-glucopyranosidePrednicarbate
go.drugbank.com/drugs/DB01130ApprovedIL-1a is also found in fibroblasts, where it is responsible for proliferation, collagenase induction and IL-6 synthesis, which are related to skin thickness. … It is used in the treatment of inflammatory skin diseases, such as atopic dermatitis.
Products: PREDNITOP SALBE, PREDNICARBAT ACIS SALBETuberculin purified protein derivative
go.drugbank.com/drugs/DB11601ApprovedTuberculin Purified Protein Derivative (PPD) is a sterile aqueous solution of a purified protein fraction for intradermal administration as an aid in the diagnosis of tuberculosis. … The diagnostic test is commonly referred to as the Mantoux test which serves to minimize the risk of transmission of infection with *Mycobacterium tuberculosis* through early diagnosis and appropriate
Categories: Compounds used in a research, industrial, or household settingProducts: BIOCINE TESTPPD 5-UI/ 01 ML, Tuberculin PPD RT 23 AJV