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Displaying results 551 - 560 of 10000 in total
  1. Drug

    Rasagiline

    go.drugbank.com/drugs/DB01367
    ApprovedInvestigational

    Rasagiline is an irreversible inhibitor of monoamine oxidase and is used as a monotherapy in early Parkinson's disease or as an adjunct therapy in more advanced cases.

    Categories: Compounds used in a research, industrial, or household settingSynonyms: (1R)-N-propargylindan-1-amine, (R)-N-2-Propynyl-1-indanamine
  2. Drug

    Carbamide peroxide

    go.drugbank.com/drugs/DB11129
    ApprovedInvestigational

    As it is a source of hydrogen peroxide, it can be found in disinfecting and dental bleaching products. … of this ingredient as an oral wound healing agent [L1976].

    Categories: Compounds used in a research, industrial, or household settingInternational brands: Sential E
  3. Drug

    Ivabradine

    go.drugbank.com/drugs/DB09083
    ApprovedInvestigational

    Ivabradine acts by selectively inhibiting the "funny" channel pacemaker current (If) in the sinoatrial node in a dose-dependent fashion, resulting in a lower heart rate and thus more blood to flow to the … Therefore, as ivabradine is designed as a "pure" heart rate-lowering drug by selectively acting on the If channels, it may offer a more favorable side effect profile due to its lower likelihood of causing

    Products: IVABRADINA EG, IVABRADIN AL 5MG
  4. Drug

    Omeprazole

    go.drugbank.com/drugs/DB00338
    ApprovedInvestigationalVet approved

    Originally approved by the FDA in 1989, omeprazole is a _proton-pump inhibitor_, used to treat gastric acid-related disorders. … Omeprazole is generally effective and well-tolerated, promoting its popular use in children and adults [FDA label].

    Products: OMEPRAZOLO EG STADA, OMEPRADEX EC TABLET 20mg
  5. Drug

    Tamoxifen

    go.drugbank.com/drugs/DB00675
    ApprovedInvestigational

    Tamoxifen is a non-steroidal antiestrogen used to treat estrogen receptor positive breast cancers as well as prevent the incidence of breast cancer in high risk populations. … [A1025,L7799,L7802] Tamoxifen is used alone or as an adjuvant in these treatments.

    Categories: UGT2B7 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic IndexSynonyms: 1-p-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene, 1-para-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene
  6. Drug

    Urea

    go.drugbank.com/drugs/DB03904
    ApprovedInvestigational

    A compound formed in the liver from ammonia produced by the deamination of amino acids. … It is the principal end product of protein catabolism and constitutes about one half of the total urinary solids.

    Mixtures: HYDROCORTISONE 1% ET UREA 5% CREAM, Ti-U-lac LotionProducts: Rea Lo 39, Rea Lo 40
  7. Drug

    Benzoyl peroxide

    go.drugbank.com/drugs/DB09096
    ApprovedInvestigational

    Benzoyl peroxide is a commonly used drug in topical treatments for acne. … [A234059,A234064,A234069] Benzoyl peroxide, in combination with erythromycin, was granted FDA approval on 26 October 1984.[L33264]

    Mixtures: Clean and Clear Advantage 2-in-1 Acne and Mark Eraser KitProducts: La Roche Posay Laboratoire DermatologiqueEffaclar Duo, La Roche-Posay Effaclar Duo Dual Action Acne Treatment
  8. Drug

    Methotrexate

    go.drugbank.com/drugs/DB00563
    ApprovedInvestigational

    [A180322,L7144,L7147,L7150,L7180] Due to the toxic effects of methotrexate, it is indicated for treatment of some forms of arthritis and severe psoriasis only if first line treatment has failed or patients … [L7180] Methotrexate was granted FDA approval on 7 December 1953.[L7198]

    Categories: OAT3/SLC22A8 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic IndexSynonyms: N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid, 4-amino-N(10)-methylpteroylglutamic acid
  9. Drug

    Citalopram

    go.drugbank.com/drugs/DB00215
    ApprovedInvestigational

    [A261316,A14720] Specifically, it has a very minimal effect on dopamine and norepinephrine transportation and virtually no affinity for muscarinic, histaminergic, or GABAergic receptors. … [A261316] Citalopram was approved by the FDA in 1998 for the treatment of depression in adults 18 years or older.[L5230]

    Categories: Monoamine Oxidase A SubstratesProducts: CITALOPRAM EG, CITALOPRAM EG STADA
  10. Drug

    Ribitol

    go.drugbank.com/drugs/DB14704
    Investigational

    Synonyms: L-ribitol, (2R,3s,4S)-pentane-1,2,3,4,5-pentol