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Molindone
go.drugbank.com/drugs/DB01618ApprovedMolindone has much lower affinity for D2 receptors than most antipsychotic agents and has a relatively low affinity for D1 receptors. … An indole derivative effective in schizophrenia and other psychoses and possibly useful in the treatment of the aggressive type of undersocialized conduct disorder.
Categories: Dopamine D2 Receptor AntagonistsPhenylpropanolamine
go.drugbank.com/drugs/DB00397ApprovedVet approvedWithdrawnCurrently, it is withdrawn from the market in Canada and the United States due to the risk for hemorrahgic strokes.
Mixtures: Emercidin D Tab, Pharmacol DM SyrBromhexine
go.drugbank.com/drugs/DB09019ApprovedInvestigationalIt was introduced into the market in 1963, and is widely available as an over-the-counter drug in many countries. … [A233240] Recently, bromhexine and its metabolite [ambroxol] have garnered interest for the potential prevention and treatment of COVID-19 due to their interactions with cell receptors in the lungs.
Mixtures: TUSSIONEX DUO JARABE, Hosolvon DM Elixir (Sugar Free)Aluminum zirconium octachlorohydrex gly
go.drugbank.com/drugs/DB11200ApprovedIt is an active antiperspirant agent [L2705], [L2706]. It diffuses into the sweat pores and prevents perspiration (sweat) from leaving the pores.
Products: Dr. Nona, Secret Pasion de Tango ClearCertolizumab pegol
go.drugbank.com/drugs/DB08904ApprovedInvestigational[A176585] It is formed with a humanized Fab fragment of 50 kDa, from an IgG 1 isotype, fused to a 40 kDa polyethylene glycol moiety replacing the Fc antibody region. … [A176606] Certolizumab does not require glycosylation for active function and hence, its production is significantly more affordable when compared to other existing TNF-alpha therapies as it can be
Vandetanib
go.drugbank.com/drugs/DB05294ApprovedInvestigationalVandetanib is an oral once-daily kinase inhibitor of tumour angiogenesis and tumour cell proliferation with the potential for use in a broad range of tumour types.
Icosapent ethyl
go.drugbank.com/drugs/DB08887ApprovedInvestigationalNutraceuticalIt is used as an adjunct therapy for severe hypertriglyceridemia (TG levels > 500 mg/dL) and to reduce the risk of cardiovascular events in certain patients with elevated triglycerides.
Omega-3-acid ethyl esters
go.drugbank.com/drugs/DB09539ApprovedInvestigationalcontain eicosapentaenoic acid-ethyl ester (EPA) and docosahexaenoic acid-ethyl ester (DHA) that are used in combination with changes in diet to lower triglyceride levels in adults with severe (≥ 500 mg/dL … Omega-3-acid ethyl esters are currently marketed in the US, EU, and many other regions under the brand name Lovaza[FDA Label][L5849].
Dimetindene
go.drugbank.com/drugs/DB08801ApprovedInvestigationalDimetindene (Fenistil) is an antihistamine/anticholinergic used orally and locally as an antipruritic.
Eluxadoline
go.drugbank.com/drugs/DB09272ApprovedInvestigationalof both pain and diarrhea characteristic of IBS-D. … Eluxadoline is a mixed mu-opioid receptor agonist, kappa-opioid receptor agonist, and a-delta opioid receptor antagonist indicated for use in diarrhea-predominant irritable bowel syndrome (IBS-D).
Categories: mu-Opioid Receptor Agonist