Search

Displaying results 5591 - 5600 of 10000 in total
  1. Target

    Deoxynucleoside triphosphate triphosphohydrolase SAMHD1

    go.drugbank.com/bio_entities/BE0021514
    EnzymeHumans

    Not able to restrict infection by HIV-2 virus; because restriction activity is counteracted by HIV-2 viral protein Vpx (PubMed:21613998, PubMed:21720370).

    Synonyms: SAM domain and HD domain-containing protein 1
  2. Indication

    Glioblastomas

    go.drugbank.com/conditions/DBCOND0043840
    Drugs: Carmustine · Irinotecan · Temozolomide
    Synonyms: Glioblastoma, NOS, [M]Glioblastoma NOS
  3. Drug

    Nanoparticle Epirubicin

    go.drugbank.com/drugs/DB16248
    Investigational

    Nanoparticle Epirubicin is under investigation in clinical trial NCT03168061 (Dose-escalation and Expansion Trial of NC-6300 in Patients With Advanced Solid Tumors or Soft Tissue Sarcoma).

  4. Drug

    Glumetinib

    go.drugbank.com/drugs/DB15630
    Investigational

    Glumetinib is under investigation in clinical trial NCT04270591 (Assess the Anti-tumor Activity and Safety of Glumetinib in Patient With Advanced C-met-positive Non-small Cell Lung Cancer).

  5. Drug

    Menotropins

    go.drugbank.com/drugs/DB00032
    ApprovedInvestigational

    Menotropins contains follicle stimulating hormone (FSH) and luteinizing hormone (LH) purified from the urine of postmenopausal women. It is used as a fertility medication that is injected either subcutaneously or intramuscularly. It is c...

  6. Drug

    Pictilisib

    go.drugbank.com/drugs/DB11663
    Investigational

    Pictilisib has been used in trials studying the treatment of Solid Cancers, Breast Cancer, Advanced Solid Tumours, Metastatic Breast Cancer, and Non-Hodgkin's Lymphoma, Solid Cancers, among others.

  7. Drug

    Fazpilodemab

    go.drugbank.com/drugs/DB18924
    Investigational

    Fazpilodemab is under investigation in clinical trial NCT04171765 (A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of BFKB8488A Compared With Placebo in Participants With Non-alcoholic Steatohepatitis

  8. Drug

    Geneticin

    go.drugbank.com/drugs/DB04263
    Experimental

    Resistance to Geneticin is conferred by the neo gene from Tn5 encoding an aminoglycoside 3‘-phosphotransferase, APH 3‘ II. … Geneticin (also known as G418) is an aminoglycoside antibiotic similar in structure to gentamicin B1, produced by Micromonospora rhodorangea.

  9. Drug

    TAK-428

    go.drugbank.com/drugs/DB05499
    Experimental

    It is based on the novel concept that peripheral nervous tissue that was damaged by diabetes can be repaired and regenerated by stimulating an increase in neurotrophic factors.

  10. Drug

    Surotomycin

    go.drugbank.com/drugs/DB12076
    Investigational

    Surotomycin is non-inferior to vancomycin and offers a promising alternative for the treatment and prevention of C. diff infection. … It is a benzenebutanoic acid derivative patented by Cubist Pharmaceuticals, Inc. as antibacterial agents for the treatment of Gram-positive infections.