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Displaying results 561 - 570 of 7555 in total
  1. Drug

    Nimodipine

    go.drugbank.com/drugs/DB00393
    ApprovedInvestigational

    It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. … By inhibiting the influx of calcium in smooth muscle cells, nimodipine prevents calcium-dependent smooth muscle contraction and subsequent vasoconstriction.

  2. Drug

    Escitalopram

    go.drugbank.com/drugs/DB01175
    ApprovedInvestigational

    to other SSRIs. … as compared to other agents in this class.

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: NEO ZENTIUS® 10 MG, NEO ZENTIUS® 20 MG COMPRIMIDOS
  3. Drug

    Cemiplimab

    go.drugbank.com/drugs/DB14707
    ApprovedInvestigational

    By blocking PD-1, cemiplimab works to enhance T cell-mediated antitumour responses. … [L39804] Cemiplimab was also approved by the European Commission on June 28, 2019.

  4. Indication

    Lymphoblastic Lymphoma

    go.drugbank.com/conditions/DBCOND0032667
    Drugs: Asparaginase Erwinia chrysanthemi · Mercaptopurine
    Synonyms: Non-Hodgkin lymphoma, no ICD-O subtype, Non-Hodgkin lymphoma, no ICD-O subtype (morphologic abnormality)
  5. Drug

    Camphor

    go.drugbank.com/drugs/DB01744
    ApprovedInvestigationalWithdrawn

    The FDA ruled that camphorated oil could not be marketed in the United States and that no product could contain a concentration higher than 11%.

    Mixtures: Zam-Buk Ointment, Pharmacys Prescription Vapor RubProducts: Just Cbd Roll-ON Warming, Pain Relief Roll-On Muscle
  6. Indication

    Diabetes Mellitus, Insulin Dependent

    go.drugbank.com/conditions/DBCOND0035532
    Drugs: Insulin pork
    Synonyms: Diabetes mellitus: [juvenile type, with no mention of complication] or [insulin dependent]
  7. Indication

    Hearing loss or impairment

    go.drugbank.com/conditions/DBCOND0094276
    Drugs: Almitrine · Levosulpiride
    Synonyms: No hearing
  8. Drug

    Ruxolitinib

    go.drugbank.com/drugs/DB08877
    ApprovedInvestigational

    By inhibiting JAK1 and JAK2, ruxolitinib works to block the dysregulated cell signalling pathways and prevents abnormal blood cell proliferation. … [A229883] Ruxolitinib has been investigated to treat patients with coronavirus disease 2019 (COVID-19) accompanied by severe systemic hyperinflammation.

  9. Drug

    Bremelanotide

    go.drugbank.com/drugs/DB11653
    Approved

    [A179683] Since then it was investigated for its place in treating sexual dysfunction in men and women but is now only indicated for women. … [A179686] The mechanism by which bremelanotide's action on receptors translates to a clinical effect is still unknown.

  10. Drug

    Dydrogesterone

    go.drugbank.com/drugs/DB00378
    ApprovedInvestigationalWithdrawn

    A synthetic progestational hormone with no androgenic or estrogenic properties. … Unlike many other progestational compounds, dydrogesterone produces no increase in temperature and does not inhibit ovulation.